2. Autophagy Metabolic Enzyme/Protease
  3. Autophagy Endogenous Metabolite
  4. Niacin-d4

Niacin-d4  (Synonyms: Nicotinic acid-d4; Vitamin B3-d4)

Cat. No.: HY-B0143S2 Purity: 99.15%
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Niacin-d4 is the deuterium labeled Niacin. Niacin (Nicotinic acid) is a vitamin and is part of the vitamin B group.

For research use only. We do not sell to patients.

Niacin-d<sub>4</sub> Chemical Structure

Niacin-d4 Chemical Structure

CAS No. : 66148-15-0

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1 mg USD 90 In-stock
5 mg USD 350 In-stock
10 mg USD 650 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Niacin-d4:

Niacin-d4 Related Antibodies

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Description

Niacin-d4 is the deuterium labeled Niacin. Niacin (Nicotinic acid) is a vitamin and is part of the vitamin B group.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Niacin-d4 Related Antibodies
Molecular Weight

127.13

Formula

C6HD4NO2
CAS No.
Unlabeled CAS

59-67-6
Appearance

Solid

Color

White to off-white

SMILES

OC(C1=C([2H])N=C([2H])C([2H])=C1[2H])=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 83.33 mg/mL (655.47 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 7.8660 mL 39.3298 mL 78.6596 mL
5 mM 1.5732 mL 7.8660 mL 15.7319 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

V1

=
Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 7.8660 mL 39.3298 mL 78.6596 mL 196.6491 mL
5 mM 1.5732 mL 7.8660 mL 15.7319 mL 39.3298 mL
10 mM 0.7866 mL 3.9330 mL 7.8660 mL 19.6649 mL
15 mM 0.5244 mL 2.6220 mL 5.2440 mL 13.1099 mL
20 mM 0.3933 mL 1.9665 mL 3.9330 mL 9.8325 mL
25 mM 0.3146 mL 1.5732 mL 3.1464 mL 7.8660 mL
30 mM 0.2622 mL 1.3110 mL 2.6220 mL 6.5550 mL
40 mM 0.1966 mL 0.9832 mL 1.9665 mL 4.9162 mL
50 mM 0.1573 mL 0.7866 mL 1.5732 mL 3.9330 mL
60 mM 0.1311 mL 0.6555 mL 1.3110 mL 3.2775 mL
80 mM 0.0983 mL 0.4916 mL 0.9832 mL 2.4581 mL
100 mM 0.0787 mL 0.3933 mL 0.7866 mL 1.9665 mL
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Niacin-d4 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Niacin-d466148-15-0Nicotinic acid-d4Vitamin B3-d4AutophagyEndogenous MetaboliteInhibitorinhibitorinhibit

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