Niflumic acid (Standard)

Cat. No.: HY-B0493R Purity: ≥98%: FAQs
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Niflumic acid (Standard) is the analytical standard of Niflumic acid. This product is intended for research and analytical applications. Niflumic acid is a calcium-activated chloride channel blocker and COX-2 inhibitor with the IC₅₀ value of 100 nM. Niflumic acid induces apoptosis through caspase-8/Bid/Bax pathway in lung cancer cells. Niflumic acide exhibits anti-tumor activity by affecting the expression of ERK1/2 and the activity of MMP2 and MMP9. Niflumic acid has orally bioactivity. Niflumic acid acts on rheumatoid arthritis.

For research use only. We do not sell to patients.

Niflumic acid (Standard) Chemical Structure

CAS No. : 4394-00-7

Size	Price	Stock
10 mg	USD 48	Ask For Quote & Lead Time
25 mg	USD 88	Ask For Quote & Lead Time
50 mg	USD 133	Ask For Quote & Lead Time
100 mg	USD 200	Ask For Quote & Lead Time

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Description	Niflumic acid (Standard) is the analytical standard of Niflumic acid . This product is intended for research and analytical applications. Niflumic acid is a calcium-activated chloride channel blocker and COX-2 inhibitor with the IC₅₀ value of 100 nM. Niflumic acid induces apoptosis through caspase-8/Bid/Bax pathway in lung cancer cells. Niflumic acid e exhibits anti-tumor activity by affecting the expression of ERK1/2 and the activity of MMP2 and MMP9. Niflumic acid has orally bioactivity. Niflumic acid acts on rheumatoid arthritis.
Molecular Weight	282.22
Formula	C₁₃H₉F₃N₂O₂
CAS No.	4394-00-7
Appearance	Solid
Color	Off-white to light yellow
SMILES	O=C(C1=CC=CN=C1NC2=CC=CC(C(F)(F)F)=C2)O
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Handling Instructions (2659 KB)

Niflumic acid (Standard) Related Classifications

Inflammation/Immunology

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Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Niflumic acid (Standard)4394-00-7Chloride ChannelCOXCl− Channels CyclooxygenaseNiflumic AcidChloride Channel/COX InhibitorInhibitorinhibitorinhibit

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Niflumic acid (Standard)

Product Information

Purity & Documentation

Customer Review