2. Immunology/Inflammation
  3. NOD-like Receptor (NLR)
  4. NLRP3-IN-21

NLRP3-IN-21 (compound L38) is a NLRP3 inflammasome inhibitor with inflammatory properties. NLRP3-IN-21 inhibits NLRP3 inflammasome activation and pyroptosis by suppressing gasdermin D cleavage, ASC oligomerization, and NLRP3 inflammasome assembly.

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NLRP3-IN-21 Chemical Structure

NLRP3-IN-21 Chemical Structure

CAS No. : 2956791-61-8

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NLRP3-IN-21 Related Antibodies

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Description

NLRP3-IN-21 (compound L38) is a NLRP3 inflammasome inhibitor with inflammatory properties. NLRP3-IN-21 inhibits NLRP3 inflammasome activation and pyroptosis by suppressing gasdermin D cleavage, ASC oligomerization, and NLRP3 inflammasome assembly[1].

Molecular Weight

529.32

Formula

C20H13Cl2F3N6O2S
CAS No.
SMILES

O=C1N(N=C(N2C1=CC3=C2C=C(S3)Cl)C(C)C)CC4=NN=C(O4)C5=CC=C(N=C5Cl)C(F)(F)F
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Purity & Documentation
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NLRP3-IN-21 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NLRP3-IN-212956791-61-8NOD-like Receptor (NLR)NACHT domainNLRP3 Inflammasomegasdermin DASC oligomerizationInhibitorinhibitorinhibit

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