2. Protein Tyrosine Kinase/RTK PI3K/Akt/mTOR Stem Cell/Wnt MAPK/ERK Pathway JAK/STAT Signaling GPCR/G Protein
  3. Akt VEGFR STAT Ras
  4. Notoginsenoside R4

Notoginsenoside R4 is a ginsenoside that can be isolated from ginseng roots. In the molecular docking results, Notoginsenoside R4 can target STAT3, AKT1, HRAS, VEGFA and CASP3.

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Notoginsenoside R4 Chemical Structure

Notoginsenoside R4 Chemical Structure

CAS No. : 87741-77-3

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Notoginsenoside R4 Related Antibodies

Top Publications Citing Use of Products

View All Akt Isoform Specific Products:

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Akt Akt1 Akt2 Akt3

View All VEGFR Isoform Specific Products:

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VEGFR1/Flt-1 VEGFR2/KDR/Flk-1 VEGFR3/Flt-4

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STAT3 STAT5 STAT6 STAT1

View All Ras Isoform Specific Products:

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K-Ras H-Ras N-Ras Ras

  • Biological Activity

  • Purity & Documentation

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Description

Notoginsenoside R4 is a ginsenoside that can be isolated from ginseng roots. In the molecular docking results, Notoginsenoside R4 can target STAT3, AKT1, HRAS, VEGFA and CASP3[1][2].

Molecular Weight

1241.41

Formula

C59H100O27
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C[C@@]([C@@]([C@@]1([H])[C@@]2([H])[C@@](CC/C=C(C)/C)(C)O[C@@H]([C@@H]([C@H]3O)O)O[C@@H]([C@H]3O)CO[C@@H]([C@@H]([C@H]4O)O)O[C@@H]([C@H]4O)CO[C@H](OC[C@H]5O)[C@@H]([C@H]5O)O)(CC2)C)(CC[C@@]6([H])C7(C)C)[C@@](C[C@H]1O)([H])[C@]6(CC[C@@H]7O[C@H](O[C@@H]8CO)[C@@H]([C@H]([C@@H]8O)O)O[C@@H]([C@@H]([C@H]9O)O)O[C@@H]([C@H]9O)CO)C
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 5 mg/mL (4.03 mM; Need ultrasonic and warming)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.8055 mL 4.0277 mL 8.0554 mL
5 mM --- --- ---
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Purity & Documentation

Purity: 99.84%

Data Sheet (284 KB) SDS (251 KB)

COA (268 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 0.8055 mL 4.0277 mL 8.0554 mL 20.1384 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Notoginsenoside R4 Related Classifications

Keywords:

Notoginsenoside R487741-77-3Notoginsenoside R 4Notoginsenoside R-4AktVEGFRSTATRasPKBProtein kinase BVascular endothelial growth factor receptorGinsenosideNatural productginsengInhibitorinhibitorinhibit

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