1. Apoptosis
  2. MDM-2/p53
  3. NSC405640

NSC405640 is a potent inhibitor of the MDM2-p53 interaction. NSC405640 rescues structural p53 mutations. NSC405640 selectively inhibits the growth of cell lines with wild-type p53.

For research use only. We do not sell to patients.

NSC405640 Chemical Structure

NSC405640 Chemical Structure

CAS No. : 1135-99-5

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Description

NSC405640 is a potent inhibitor of the MDM2-p53 interaction. NSC405640 rescues structural p53 mutations. NSC405640 selectively inhibits the growth of cell lines with wild-type p53[1].

Molecular Weight

343.82

Formula

C12H10Cl2Sn

CAS No.
SMILES

Cl[Sn](C1=CC=CC=C1)(C2=CC=CC=C2)Cl

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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NSC405640
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HY-144105
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