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NSI-189 phosphate is the phosphate salt form of NSI-189 (HY-13999). NSI-189 phosphate stimulates the neurogenesis of neural stem cells. NSI-189 phosphate exhibits neuroprotective effect in Streptozotocin (HY-13753)-induced diabetic mouse model, improves neurological function and cognitive ability after stroke in rat middle cerebral artery occlusion (MCAo) model, and exhibits antidepressant efficacy.

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NSI-189 phosphate Chemical Structure

NSI-189 phosphate Chemical Structure

CAS No. : 1270138-41-4

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Description

NSI-189 phosphate is the phosphate salt form of NSI-189 (HY-13999). NSI-189 phosphate stimulates the neurogenesis of neural stem cells. NSI-189 phosphate exhibits neuroprotective effect in Streptozotocin (HY-13753)-induced diabetic mouse model, improves neurological function and cognitive ability after stroke in rat middle cerebral artery occlusion (MCAo) model, and exhibits antidepressant efficacy[1].

Molecular Weight

464.49

Formula

C22H33N4O5P

CAS No.
SMILES

O=C(N1CCN(CC1)CC2=CC=CC=C2)C3=CC=CN=C3NCCC(C)C.O=P(O)(O)O

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NSI-189 phosphate Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
NSI-189 phosphate
Cat. No.:
HY-13999A1
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