2. Metabolic Enzyme/Protease
  3. CETP
  4. Obicetrapib

Obicetrapib  (Synonyms: TA-8995; DEZ-001)

Cat. No.: HY-18778 Purity: 98.95%
SDS COA Handling Instructions Technical Support

TA-8995 is a new and selective cholesteryl ester transfer protein (CETP) inhibitor.

For research use only. We do not sell to patients.

Obicetrapib Chemical Structure

Obicetrapib Chemical Structure

CAS No. : 866399-87-3

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Based on 1 publication(s) in Google Scholar

Obicetrapib Related Antibodies

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Description

TA-8995 is a new and selective cholesteryl ester transfer protein (CETP) inhibitor.

Molecular Weight

722.60

Formula

C32H31F9N4O5
CAS No.
Appearance

Solid

Color

White to light yellow

SMILES

FC(F)(F)C1=CC(C(F)(F)F)=CC(CN(C2=NC=C(OCCCC(O)=O)C=N2)[C@@H]3C4=CC(C(F)(F)F)=CC=C4N([C@@H](C3)CC)C(OCC)=O)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (172.99 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.3839 mL 6.9195 mL 13.8389 mL
5 mM 0.2768 mL 1.3839 mL 2.7678 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.3839 mL 6.9195 mL 13.8389 mL 34.5973 mL
5 mM 0.2768 mL 1.3839 mL 2.7678 mL 6.9195 mL
10 mM 0.1384 mL 0.6919 mL 1.3839 mL 3.4597 mL
15 mM 0.0923 mL 0.4613 mL 0.9226 mL 2.3065 mL
20 mM 0.0692 mL 0.3460 mL 0.6919 mL 1.7299 mL
25 mM 0.0554 mL 0.2768 mL 0.5536 mL 1.3839 mL
30 mM 0.0461 mL 0.2306 mL 0.4613 mL 1.1532 mL
40 mM 0.0346 mL 0.1730 mL 0.3460 mL 0.8649 mL
50 mM 0.0277 mL 0.1384 mL 0.2768 mL 0.6919 mL
60 mM 0.0231 mL 0.1153 mL 0.2306 mL 0.5766 mL
80 mM 0.0173 mL 0.0865 mL 0.1730 mL 0.4325 mL
100 mM 0.0138 mL 0.0692 mL 0.1384 mL 0.3460 mL
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Obicetrapib Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Obicetrapib866399-87-3TA-8995 DEZ-001TA8995TA 8995DEZ001DEZ 001DEZ-001CETPCholesteryl ester transfer proteinInhibitorinhibitorinhibit

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