2. Metabolic Enzyme/Protease
  3. Tyrosinase
  4. Obtusifolin-2-O-glucoside

Obtusifolin-2-O-glucoside (compound 7) is a Tyrosinase inhibitor (IC50=9.2 μM). Obtusifolin-2-O-glucoside can be isolated from cassia seed.

For research use only. We do not sell to patients.

Obtusifolin-2-O-glucoside Chemical Structure

Obtusifolin-2-O-glucoside Chemical Structure

CAS No. : 120163-18-0

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Based on 1 publication(s) in Google Scholar

Obtusifolin-2-O-glucoside Related Antibodies

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Description

Obtusifolin-2-O-glucoside (compound 7) is a Tyrosinase inhibitor (IC50=9.2 μM). Obtusifolin-2-O-glucoside can be isolated from cassia seed[1].

IC50 & Target

IC50: 9.2 μM (Tyrosinase)[1]
In Vitro

Obtusifolin-2-O-glucoside (compound 7) (10 μM; 48 h) inhibits melanin production in α-MSH-treated B16F10 melanoma cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Obtusifolin-2-O-glucoside Related Antibodies
Molecular Weight

446.40

Formula

C22H22O10
CAS No.
Appearance

Solid

Color

Yellow to brown

SMILES

COC1=C2C(C(C3=CC=CC(O)=C3C2=O)=O)=CC(C)=C1O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)CO
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (56.00 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2401 mL 11.2007 mL 22.4014 mL
5 mM 0.4480 mL 2.2401 mL 4.4803 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.2401 mL 11.2007 mL 22.4014 mL 56.0036 mL
5 mM 0.4480 mL 2.2401 mL 4.4803 mL 11.2007 mL
10 mM 0.2240 mL 1.1201 mL 2.2401 mL 5.6004 mL
15 mM 0.1493 mL 0.7467 mL 1.4934 mL 3.7336 mL
20 mM 0.1120 mL 0.5600 mL 1.1201 mL 2.8002 mL
25 mM 0.0896 mL 0.4480 mL 0.8961 mL 2.2401 mL
30 mM 0.0747 mL 0.3734 mL 0.7467 mL 1.8668 mL
40 mM 0.0560 mL 0.2800 mL 0.5600 mL 1.4001 mL
50 mM 0.0448 mL 0.2240 mL 0.4480 mL 1.1201 mL
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Obtusifolin-2-O-glucoside Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Obtusifolin-2-O-glucoside120163-18-0TyrosinaseInhibitorinhibitorinhibit

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