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  4. Orbofiban acetate

Orbofiban acetate is an orally active platelet GPIIb/IIIa antagonist that inhibits platelet aggregation.

For research use only. We do not sell to patients.

Orbofiban acetate Chemical Structure

Orbofiban acetate Chemical Structure

CAS No. : 163250-91-7

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1 mg USD 260 In-stock
5 mg USD 650 In-stock
10 mg USD 1050 In-stock
25 mg USD 2140 In-stock
50 mg USD 3400 In-stock
100 mg USD 5500 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Orbofiban acetate:

Orbofiban acetate Related Antibodies

Top Publications Citing Use of Products

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αvβ1 αvβ3 αvβ5 αvβ6 αvβ8 α5β1 α1β1 α2β1 α4β1 α9β1 αIIbβ3 α4β7 αLβ2

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  • Purity & Documentation

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Description

Orbofiban acetate is an orally active platelet GPIIb/IIIa antagonist that inhibits platelet aggregation.

IC50 & Target

GPIIb/IIIa

 

Molecular Weight

421.45

Formula

C19H27N5O6
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C1N(C(C=C2)=CC=C2C(N)=N)CC[C@@H]1NC(NCCC(OCC)=O)=O.CC(O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, stored under nitrogen, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 150 mg/mL (355.91 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3728 mL 11.8638 mL 23.7276 mL
5 mM 0.4746 mL 2.3728 mL 4.7455 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

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g

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.3728 mL 11.8638 mL 23.7276 mL 59.3190 mL
5 mM 0.4746 mL 2.3728 mL 4.7455 mL 11.8638 mL
10 mM 0.2373 mL 1.1864 mL 2.3728 mL 5.9319 mL
15 mM 0.1582 mL 0.7909 mL 1.5818 mL 3.9546 mL
20 mM 0.1186 mL 0.5932 mL 1.1864 mL 2.9660 mL
25 mM 0.0949 mL 0.4746 mL 0.9491 mL 2.3728 mL
30 mM 0.0791 mL 0.3955 mL 0.7909 mL 1.9773 mL
40 mM 0.0593 mL 0.2966 mL 0.5932 mL 1.4830 mL
50 mM 0.0475 mL 0.2373 mL 0.4746 mL 1.1864 mL
60 mM 0.0395 mL 0.1977 mL 0.3955 mL 0.9887 mL
80 mM 0.0297 mL 0.1483 mL 0.2966 mL 0.7415 mL
100 mM 0.0237 mL 0.1186 mL 0.2373 mL 0.5932 mL
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Orbofiban acetate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Orbofiban163250-91-7IntegrinInhibitorinhibitorinhibit

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