1. Oxadiargyl

Oxadiargyl  (Synonyms: RP-020630)

Cat. No.: HY-122319 Purity: 99.94%
SDS COA Handling Instructions

Oxadiargyl (RP-020630) is an herbicide that inhibits protoporphyrinogen oxidase and has both pre- and early post-emergent weed activity. Oxadiargyl (RP-020630) has a short residual activity period, broad weed spectrum, and can be used in various soil types.

For research use only. We do not sell to patients.

Oxadiargyl Chemical Structure

Oxadiargyl Chemical Structure

CAS No. : 39807-15-3

Size Price Stock Quantity
5 mg USD 34 In-stock
10 mg USD 52 In-stock
25 mg USD 90 In-stock
50 mg USD 135 In-stock
100 mg USD 200 In-stock
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Description

Oxadiargyl (RP-020630) is an herbicide that inhibits protoporphyrinogen oxidase and has both pre- and early post-emergent weed activity. Oxadiargyl (RP-020630) has a short residual activity period, broad weed spectrum, and can be used in various soil types[1][2].

Molecular Weight

341.19

Formula

C15H14Cl2N2O3

CAS No.
Appearance

Solid

Color

Off-white to light brown

SMILES

O=C1OC(C(C)(C)C)=NN1C2=CC(OCC#C)=C(C=C2Cl)Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (146.55 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9309 mL 14.6546 mL 29.3092 mL
5 mM 0.5862 mL 2.9309 mL 5.8618 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% Saline

    Solubility: ≥ 2.5 mg/mL (7.33 mM); Clear solution

    This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).

    Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.

    Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
%
DMSO +
+
%
Tween-80 +
%
Saline
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Calculation results:
Working solution concentration: mg/mL
Method for preparing stock solution: mg drug dissolved in μL  DMSO (Stock solution concentration: mg/mL).

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).
Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.
 If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.9309 mL 14.6546 mL 29.3092 mL 73.2730 mL
5 mM 0.5862 mL 2.9309 mL 5.8618 mL 14.6546 mL
10 mM 0.2931 mL 1.4655 mL 2.9309 mL 7.3273 mL
15 mM 0.1954 mL 0.9770 mL 1.9539 mL 4.8849 mL
20 mM 0.1465 mL 0.7327 mL 1.4655 mL 3.6636 mL
25 mM 0.1172 mL 0.5862 mL 1.1724 mL 2.9309 mL
30 mM 0.0977 mL 0.4885 mL 0.9770 mL 2.4424 mL
40 mM 0.0733 mL 0.3664 mL 0.7327 mL 1.8318 mL
50 mM 0.0586 mL 0.2931 mL 0.5862 mL 1.4655 mL
60 mM 0.0488 mL 0.2442 mL 0.4885 mL 1.2212 mL
80 mM 0.0366 mL 0.1832 mL 0.3664 mL 0.9159 mL
100 mM 0.0293 mL 0.1465 mL 0.2931 mL 0.7327 mL
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Oxadiargyl Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Oxadiargyl
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