2. Cell Cycle/DNA Damage Cytoskeleton Antibody-drug Conjugate/ADC Related
  3. Microtubule/Tubulin ADC Cytotoxin
  4. Paclitaxel-d5

Paclitaxel-d5 is a deuterium-labeled Paclitaxel. Paclitaxel is a naturally occurring antineoplastic agent and stabilizes tubulin polymerization[1].

For research use only. We do not sell to patients.

Paclitaxel-d<sub>5</sub> Chemical Structure

Paclitaxel-d5 Chemical Structure

CAS No. : 1129540-33-5

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1 mg USD 450 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Paclitaxel-d5:

Paclitaxel-d5 Related Antibodies

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Description

Paclitaxel-d5 is a deuterium-labeled Paclitaxel. Paclitaxel is a naturally occurring antineoplastic agent and stabilizes tubulin polymerization[1].

Molecular Weight

858.94

Formula

C47H46D5NO14
CAS No.
Unlabeled CAS

33069-62-4
Appearance

Solid

Color

White to off-white

SMILES

O=C(C1=C([2H])C([2H])=C([2H])C([2H])=C1[2H])N[C@@H](C2=CC=CC=C2)[C@H](C(O[C@@H]3C(C)=C([C@@H](OC(C)=O)C([C@@]4(C)[C@]([C@@](CO5)(OC(C)=O)[C@@]5([H])C[C@@H]4O)([H])[C@@H]6OC(C7=CC=CC=C7)=O)=O)C(C)(C)[C@@]6(O)C3)=O)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 5 mg/mL (5.82 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMF : ≥ 5 mg/mL (5.82 mM)

DMF : ≥ 5 mg/mL (5.82 mM)

DMSO : ≥ 5 mg/mL (5.82 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Ethanol : ≥ 1.5 mg/mL (1.75 mM)

Ethanol : ≥ 1.5 mg/mL (1.75 mM)

DMSO:PBS (pH 7.2) (1:10) : ≥ 0.1 mg/mL (0.12 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.1642 mL 5.8211 mL 11.6423 mL
5 mM 0.2328 mL 1.1642 mL 2.3285 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
Ethanol / Ethanol / DMSO / DMF / DMF / DMSO 1 mM 1.1642 mL 5.8211 mL 11.6423 mL 29.1056 mL
DMSO / DMF / DMF / DMSO 5 mM 0.2328 mL 1.1642 mL 2.3285 mL 5.8211 mL
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Paclitaxel-d5 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Paclitaxel-d51129540-33-5Microtubule/TubulinADC CytotoxinADC PayloadInhibitorinhibitorinhibit

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