2. GPCR/G Protein
  3. Protease Activated Receptor (PAR)
  4. PAR3 (1-6) (human)

PAR3 (1-6) is a synthetic peptide agonist of proteinase-activated receptor 1 (PAR1) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of human PAR3 and residues 39-44 of the full-length human sequence. PAR3 (1-6) activates p42/44 MAPK signaling in fibroblasts expressing PAR1, but not PAR3, an effect that can be blocked by the PAR1 antagonist RWJ 56110.

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PAR3 (1-6) (human) Chemical Structure

PAR3 (1-6) (human) Chemical Structure

CAS No. : 320347-28-2

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PAR3 (1-6) (human) Related Antibodies

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Description

PAR3 (1-6) is a synthetic peptide agonist of proteinase-activated receptor 1 (PAR1) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of human PAR3 and residues 39-44 of the full-length human sequence. PAR3 (1-6) activates p42/44 MAPK signaling in fibroblasts expressing PAR1, but not PAR3, an effect that can be blocked by the PAR1 antagonist RWJ 56110.

Molecular Weight

647.72

Formula

C29H45N9O8
CAS No.
Sequence

Thr-Phe-Arg-Gly-Ala-Pro
Sequence Shortening

TFRGAP
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Purity & Documentation
References
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PAR3 (1-6) (human) Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PAR3 (1-6) (human)320347-28-2TFRGAPProtease Activated Receptor (PAR)Thrombin receptorsInhibitorinhibitorinhibit

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