2. Apoptosis
  3. Apoptosis
  4. PBENZ-DBRMD

PBENZ-DBRMD is a potent iodothyronine deiodinase type 3 (DIO3) inhibitor. PBENZ-DBRMD has anti-proliferative activity and induces apoaptosis. PBENZ-DBRMD can be used for cancer research.

For research use only. We do not sell to patients.

PBENZ-DBRMD Chemical Structure

PBENZ-DBRMD Chemical Structure

CAS No. : 1454662-41-9

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 220 In-stock
Solution
10 mM * 1 mL in DMSO USD 220 In-stock
Solid
5 mg USD 200 In-stock
10 mg USD 330 In-stock
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Based on 1 publication(s) in Google Scholar

PBENZ-DBRMD Related Antibodies

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Description

PBENZ-DBRMD is a potent iodothyronine deiodinase type 3 (DIO3) inhibitor. PBENZ-DBRMD has anti-proliferative activity and induces apoaptosis. PBENZ-DBRMD can be used for cancer research[1].

Molecular Weight

374.97

Formula

C11H5Br2NO4
CAS No.
Appearance

Solid

Color

White to yellow

SMILES

O=C(C1=CC=C(N2C(C(Br)=C(C2=O)Br)=O)C=C1)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (266.69 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6669 mL 13.3344 mL 26.6688 mL
5 mM 0.5334 mL 2.6669 mL 5.3338 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.6669 mL 13.3344 mL 26.6688 mL 66.6720 mL
5 mM 0.5334 mL 2.6669 mL 5.3338 mL 13.3344 mL
10 mM 0.2667 mL 1.3334 mL 2.6669 mL 6.6672 mL
15 mM 0.1778 mL 0.8890 mL 1.7779 mL 4.4448 mL
20 mM 0.1333 mL 0.6667 mL 1.3334 mL 3.3336 mL
25 mM 0.1067 mL 0.5334 mL 1.0668 mL 2.6669 mL
30 mM 0.0889 mL 0.4445 mL 0.8890 mL 2.2224 mL
40 mM 0.0667 mL 0.3334 mL 0.6667 mL 1.6668 mL
50 mM 0.0533 mL 0.2667 mL 0.5334 mL 1.3334 mL
60 mM 0.0444 mL 0.2222 mL 0.4445 mL 1.1112 mL
80 mM 0.0333 mL 0.1667 mL 0.3334 mL 0.8334 mL
100 mM 0.0267 mL 0.1333 mL 0.2667 mL 0.6667 mL
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PBENZ-DBRMD Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PBENZ-DBRMD1454662-41-9Apoptosisiodothyronine deiodinase type 3anti-proliferativeanticancerInhibitorinhibitorinhibit

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