2. GPCR/G Protein Immunology/Inflammation
  3. CXCR
  4. pCXCL8-1aa

pCXCL8-1aa is an anti-inflammatory peptide. pCXCL8-1aa competitively inhibits the binding of CXCL8 to glycosaminoglycans such as heparin sulfate (HS) by binding with high affinity. This reduces the presentation of CXCL8 on the surface of vascular endothelial cells, thereby inhibiting neutrophil migration and inflammatory responses. pCXCL8-1aa can be used to study inflammatory diseases such as rheumatoid arthritis.

For research use only. We do not sell to patients.

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pCXCL8-1aa Chemical Structure

pCXCL8-1aa Chemical Structure

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pCXCL8-1aa Related Antibodies

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Description

pCXCL8-1aa is an anti-inflammatory peptide. pCXCL8-1aa competitively inhibits the binding of CXCL8 to glycosaminoglycans such as heparin sulfate (HS) by binding with high affinity. This reduces the presentation of CXCL8 on the surface of vascular endothelial cells, thereby inhibiting neutrophil migration and inflammatory responses. pCXCL8-1aa can be used to study inflammatory diseases such as rheumatoid arthritis[1].

Molecular Weight

1262.41

Formula

C55H91N17O17
Sequence

Ac-Glu-Lys-Phe-Leu-Lys-Arg-Ala-Glu-Asn-Ser-NH2
Sequence Shortening

Ac-EKFLKRAENS-NH2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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pCXCL8-1aa Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

pCXCL8-1aaCXCRCXC chemokine receptorsC-X-C motif chemokine receptorsAnti-inflammatory peptideGlycosaminoglycanRheumatoid arthritisCompetitive inhibitionCXCL8Inhibitorinhibitorinhibit

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