2. Immunology/Inflammation
  3. Complement System
  4. Pegcetacoplan acetate

Pegcetacoplan acetate is a pegylated complement C3 inhibitor peptide. Pegcetacoplan acetate acts by binding with complement component 3 (C3) and its activation fragment C3b. Pegcetacoplan acetate can be used for the research of complement-mediated diseases, including age-related macular degeneration, C3 glomerulopathy, Geographic atrophy (GA) and autoimmune haemolytic anaemia.

For research use only. We do not sell to patients.

Pegcetacoplan acetate Chemical Structure

Pegcetacoplan acetate Chemical Structure

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1 mg USD 160 In-stock
5 mg USD 400 In-stock
10 mg USD 600 In-stock
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Based on 1 publication(s) in Google Scholar

Pegcetacoplan acetate Related Antibodies

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Description

Pegcetacoplan acetate is a pegylated complement C3 inhibitor peptide. Pegcetacoplan acetate acts by binding with complement component 3 (C3) and its activation fragment C3b. Pegcetacoplan acetate can be used for the research of complement-mediated diseases, including age-related macular degeneration, C3 glomerulopathy, Geographic atrophy (GA) and autoimmune haemolytic anaemia[1][2].

Formula

(C2H4O)nC170H248N50O47S4.xC2H4O2
Appearance

Solid

Color

White to off-white

SMILES

[Pegcetacoplan (acetate)]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Purity & Documentation
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Pegcetacoplan acetate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PegcetacoplanComplement Systempegylatedcomplement C3C3bcomplement-mediated diseasesage-related macular degenerationC3 glomerulopathyGeographic atrophy (GA)autoimmune haemolytic anaemiaInhibitorinhibitorinhibit

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Pegcetacoplan acetate
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