CPP9 TFA

Cat. No.: HY-P10644A: FAQs
Data Sheet Handling Instructions

Molarity Calculator

CPP9 TFA is a small, amphipathic, cyclic cell penetrating peptide (CPP). CPPs bind directly to the plasma membrane phospholipids and enter mammalian cells via endocytosis, followed by efficient release from the endosome. CPP9 TFA can be used for intracellular delivery of therapeutic agents and chemical probes.

For research use only. We do not sell to patients.

CPP9 TFA Chemical Structure

Size	Price	Stock	Quantity
1 mg	USD 340	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 850	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 1180	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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This product is a controlled substance and not for sale in your territory.

Other Forms of CPP9 TFA:

CPP9 Get quote

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Biological Activity
Purity & Documentation
References
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Description

Molecular Weight

1553.37

Formula

C₅₉H₈₀F₁₂N₂₀O₁₆

Sequence

Cyclo({d-Phe}-{2-Nal}-Arg-{d-Arg}-Arg-{d-Arg}-Gln)

Sequence Shortening

Cyclo({d-Phe}-{2-Nal}-R-{d-Arg}-R-{d-Arg}-Q)

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility

In Vitro:

H₂O : ≥ 100 mg/mL (64.38 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	0.6438 mL	3.2188 mL	6.4376 mL
5 mM	0.1288 mL	0.6438 mL	1.2875 mL
10 mM	0.0644 mL	0.3219 mL	0.6438 mL

View the Complete Stock Solution Preparation Table

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Qian Z, et al. Discovery and Mechanism of Highly Efficient Cyclic Cell-Penetrating Peptides. Biochemistry. 2016 May 10;55(18):2601-12. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	0.6438 mL	3.2188 mL	6.4376 mL	16.0940 mL
	5 mM	0.1288 mL	0.6438 mL	1.2875 mL	3.2188 mL
	10 mM	0.0644 mL	0.3219 mL	0.6438 mL	1.6094 mL
	15 mM	0.0429 mL	0.2146 mL	0.4292 mL	1.0729 mL
	20 mM	0.0322 mL	0.1609 mL	0.3219 mL	0.8047 mL
	25 mM	0.0258 mL	0.1288 mL	0.2575 mL	0.6438 mL
	30 mM	0.0215 mL	0.1073 mL	0.2146 mL	0.5365 mL
	40 mM	0.0161 mL	0.0805 mL	0.1609 mL	0.4024 mL
	50 mM	0.0129 mL	0.0644 mL	0.1288 mL	0.3219 mL
	60 mM	0.0107 mL	0.0536 mL	0.1073 mL	0.2682 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

CPP9 TFA Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CPP9CPP 9CPP-9Otherscell penetrating peptideCPPInhibitorinhibitorinhibit

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