2. Membrane Transporter/Ion Channel
  3. CRAC Channel
  4. piCRAC-1

piCRAC-1 is a potent, photoinducible Ca2+ release-activated Ca2+ (CRAC) channel inhibitor. piCRAC-1 alleviates thrombocytopenia and hemorrhage.

For research use only. We do not sell to patients.

piCRAC-1 Chemical Structure

piCRAC-1 Chemical Structure

CAS No. : 2418049-54-2

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 286 In-stock
Solution
10 mM * 1 mL in DMSO USD 286 In-stock
Solid
5 mg USD 260 In-stock
10 mg USD 380 In-stock
25 mg USD 800 In-stock
50 mg USD 1280 In-stock
100 mg USD 2100 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

piCRAC-1 Related Antibodies

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Description

piCRAC-1 is a potent, photoinducible Ca2+ release-activated Ca2+ (CRAC) channel inhibitor. piCRAC-1 alleviates thrombocytopenia and hemorrhage[1].

Molecular Weight

384.28

Formula

C17H10F6N4
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

FC(F)(F)C(C=CC=C1F)=C1CN2N=C(C=C2)/N=N/C3=C(C=CC=C3F)F
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (260.23 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6023 mL 13.0113 mL 26.0227 mL
5 mM 0.5205 mL 2.6023 mL 5.2045 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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(per animal)

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.6023 mL 13.0113 mL 26.0227 mL 65.0567 mL
5 mM 0.5205 mL 2.6023 mL 5.2045 mL 13.0113 mL
10 mM 0.2602 mL 1.3011 mL 2.6023 mL 6.5057 mL
15 mM 0.1735 mL 0.8674 mL 1.7348 mL 4.3371 mL
20 mM 0.1301 mL 0.6506 mL 1.3011 mL 3.2528 mL
25 mM 0.1041 mL 0.5205 mL 1.0409 mL 2.6023 mL
30 mM 0.0867 mL 0.4337 mL 0.8674 mL 2.1686 mL
40 mM 0.0651 mL 0.3253 mL 0.6506 mL 1.6264 mL
50 mM 0.0520 mL 0.2602 mL 0.5205 mL 1.3011 mL
60 mM 0.0434 mL 0.2169 mL 0.4337 mL 1.0843 mL
80 mM 0.0325 mL 0.1626 mL 0.3253 mL 0.8132 mL
100 mM 0.0260 mL 0.1301 mL 0.2602 mL 0.6506 mL
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piCRAC-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

piCRAC-12418049-54-2piCRAC1piCRAC 1CRAC ChannelCalcium release-activated channelsCa2+ release-activated Ca2+ channelsstormorken syndromethrombocytopeniahemorrhageInhibitorinhibitorinhibit

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