1. GPCR/G Protein
  2. Platelet-activating Factor Receptor (PAFR)
  3. Pinusolidic acid

Pinusolidic acid is a platelet-activating factor (PAF) inhibitor with an IC50 of 23 μM.

For research use only. We do not sell to patients.

Pinusolidic acid Chemical Structure

Pinusolidic acid Chemical Structure

CAS No. : 40433-82-7

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Description

Pinusolidic acid is a platelet-activating factor (PAF) inhibitor with an IC50 of 23 μM[1].

Cellular Effect
Cell Line Type Value Description References
A549 IC50
> 40 μM
Compound: 21
Cytotoxicity against human A549 cells after 48 hrs by MTT assay
Cytotoxicity against human A549 cells after 48 hrs by MTT assay
[PMID: 23691952]
HL-60 IC50
> 40 μM
Compound: 21
Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
[PMID: 23691952]
MCF7 IC50
> 40 μM
Compound: 21
Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
[PMID: 23691952]
SMMC-7721 IC50
> 40 μM
Compound: 21
Cytotoxicity against human SMMC7721 cells after 48 hrs by MTT assay
Cytotoxicity against human SMMC7721 cells after 48 hrs by MTT assay
[PMID: 23691952]
SW480 IC50
> 40 μM
Compound: 21
Cytotoxicity against human SW480 cells after 48 hrs by MTT assay
Cytotoxicity against human SW480 cells after 48 hrs by MTT assay
[PMID: 23691952]
Vero CC50
> 750 μM
Compound: 9
Cytotoxicity against Vero E6 cells by MTT assay
Cytotoxicity against Vero E6 cells by MTT assay
[PMID: 17663539]
Vero EC50
4.71 μM
Compound: 9
Antiviral activity against SARS coronavirus in Vero E6 cells assessed as inhibition of viral replication by ELISA
Antiviral activity against SARS coronavirus in Vero E6 cells assessed as inhibition of viral replication by ELISA
[PMID: 17663539]
Molecular Weight

332.43

Formula

C20H28O4

CAS No.
SMILES

C[C@@]12[C@](CCC([C@@H]2CCC3=CCOC3=O)=C)([H])[C@](C)(CCC1)C(O)=O

Structure Classification
Initial Source

Antrodia camphorata

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Pinusolidic acid
Cat. No.:
HY-N3054
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