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  4. Platycodin A

Platycodin A is monoacetylated saponin compound isolated fromhe roots of Platycodon grandiflorum A. DC..

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Platycodin A Chemical Structure

Platycodin A Chemical Structure

CAS No. : 66779-34-8

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Based on 1 publication(s) in Google Scholar

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Description

Platycodin A is monoacetylated saponin compound isolated fromhe roots of Platycodon grandiflorum A. DC.[1].

Cellular Effect
Cell Line Type Value Description References
HCT-15 IC50
3.4 μM
Compound: 7
Antiproliferative activity against human HCT15 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human HCT15 cells after 48 hrs by sulforhodamine B assay
[PMID: 20939516]
HCT-15 IC50
4.1 μM
Compound: 7
Antiproliferative activity against human HCT15/CL02 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human HCT15/CL02 cells after 48 hrs by sulforhodamine B assay
[PMID: 20939516]
MES-SA IC50
2.3 μM
Compound: 7
Antiproliferative activity against human MESSA cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human MESSA cells after 48 hrs by sulforhodamine B assay
[PMID: 20939516]
MES-SA/Dx5 IC50
2.2 μM
Compound: 7
Antiproliferative activity against human MESSA/DX5 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human MESSA/DX5 cells after 48 hrs by sulforhodamine B assay
[PMID: 20939516]
Molecular Weight

1267.36

Formula

C59H94O29

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C([C@]([C@@H](C[C@]12C)O)(CCC3(C)C)[C@](C3)([H])C1=CC[C@@]4([H])[C@]2(CC[C@](C(CO)([C@H]5O[C@@H]([C@@H]([C@H]6O)O)O[C@@H]([C@H]6O)CO)CO)([H])[C@@]4(C[C@@H]5O)C)C)O[C@H](OC[C@@H]7O)[C@@H]([C@H]7O)O[C@H](O[C@H]8C)[C@@H]([C@@H]([C@H]8O[C@H](OC[C@H]9O)[C@@H]([C@H]9O[C@H](OC[C@@](O)%10CO)[C@@H]%10O)O)O)OC(C)=O

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Purity & Documentation
References
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Platycodin A
Cat. No.:
HY-N8922
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