2. Stem Cell/Wnt TGF-beta/Smad
  3. TGF-beta/Smad TGF-β Receptor
  4. (+)-ITD-1

(+)-ITD-1 is an inhibitor for TGF-β, that inhibits the TGF-β2 with an IC50 of 0.46 μM. (+)-ITD-1 promotes the degradation of TGF-b type II receptor (TGFBR2) and the differentiation of cardiomyocyte, and inhibits the mesoderm formation in the early differentiation stage of mouse embryonic stem cells (mESCs).

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(+)-ITD-1 Chemical Structure

(+)-ITD-1 Chemical Structure

CAS No. : 1409968-46-2

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(+)-ITD-1 Related Antibodies

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Description

(+)-ITD-1 is an inhibitor for TGF-β, that inhibits the TGF-β2 with an IC50 of 0.46 μM. (+)-ITD-1 promotes the degradation of TGF-b type II receptor (TGFBR2) and the differentiation of cardiomyocyte, and inhibits the mesoderm formation in the early differentiation stage of mouse embryonic stem cells (mESCs)[1].

Molecular Weight

415.52

Formula

C27H29NO3
CAS No.
SMILES

O=C(C([C@H](C1=CC=C(C2=CC=CC=C2)C=C1)C(C(C3)=O)=C(CC3(C)C)N4)=C4C)OCC
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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(+)-ITD-1 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(+)-ITD-11409968-46-2TGF-beta/SmadTGF-β ReceptorTransforming growth factor betaTransforming growth factor beta receptorsmESCsmesodermInhibitorinhibitorinhibit

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