2. Immunology/Inflammation
  3. FAP
  4. PNT6555

PNT6555 is a fibroblast activation protein-α (FAP) inhibitor. PNT6555 has antitumor activity. PNT6555 can be used for imaging of FAP-positive tumors.

For research use only. We do not sell to patients.

PNT6555 Chemical Structure

PNT6555 Chemical Structure

CAS No. : 2715113-34-9

Size Price Stock Quantity
1 mg USD 420 In-stock
5 mg USD 1050 In-stock
10 mg USD 1700 In-stock
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Based on 1 publication(s) in Google Scholar

PNT6555 Related Antibodies

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Description

PNT6555 is a fibroblast activation protein-α (FAP) inhibitor. PNT6555 has antitumor activity. PNT6555 can be used for imaging of FAP-positive tumors[1].

Molecular Weight

705.56

Formula

C31H48BN7O11
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC(CN1CCN(CC(NCC2=CC=C(C(N[C@@H](C(N3[C@H](B(O)O)CCC3)=O)C)=O)C=C2)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC1)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (354.33 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.4173 mL 7.0866 mL 14.1731 mL
5 mM 0.2835 mL 1.4173 mL 2.8346 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.4173 mL 7.0866 mL 14.1731 mL 35.4328 mL
5 mM 0.2835 mL 1.4173 mL 2.8346 mL 7.0866 mL
10 mM 0.1417 mL 0.7087 mL 1.4173 mL 3.5433 mL
15 mM 0.0945 mL 0.4724 mL 0.9449 mL 2.3622 mL
20 mM 0.0709 mL 0.3543 mL 0.7087 mL 1.7716 mL
25 mM 0.0567 mL 0.2835 mL 0.5669 mL 1.4173 mL
30 mM 0.0472 mL 0.2362 mL 0.4724 mL 1.1811 mL
40 mM 0.0354 mL 0.1772 mL 0.3543 mL 0.8858 mL
50 mM 0.0283 mL 0.1417 mL 0.2835 mL 0.7087 mL
60 mM 0.0236 mL 0.1181 mL 0.2362 mL 0.5905 mL
80 mM 0.0177 mL 0.0886 mL 0.1772 mL 0.4429 mL
100 mM 0.0142 mL 0.0709 mL 0.1417 mL 0.3543 mL
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PNT6555 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PNT65552715113-34-9PNT 6555PNT-6555FAPFibroblast activation proteinHEK cellsHEK cell–derived tumors expressing mouseanticancerInhibitorinhibitorinhibit

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