2. PROTAC
  3. E3 Ligase Ligand-Linker Conjugates
  4. Pomalidomide-PEG2-acetic acid

Pomalidomide-PEG2-acetic acid  (Synonyms: Pomalidomide-PEG2-CH2COOH)

Cat. No.: HY-167759
Handling Instructions Technical Support

Pomalidomide-PEG2-acetic acid (Pomalidomide-PEG2-CH2COOH) is the conjugate composed of a E3 ligase ligand and a linker. Pomalidomide-PEG2-acetic acid can be used for PROTAC synthesis.

For research use only. We do not sell to patients.

Pomalidomide-PEG2-acetic acid Chemical Structure

Pomalidomide-PEG2-acetic acid Chemical Structure

CAS No. : 2143097-05-4

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Based on 1 publication(s) in Google Scholar

Pomalidomide-PEG2-acetic acid Related Antibodies

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Description

Pomalidomide-PEG2-acetic acid (Pomalidomide-PEG2-CH2COOH) is the conjugate composed of a E3 ligase ligand and a linker. Pomalidomide-PEG2-acetic acid can be used for PROTAC synthesis[1].

Molecular Weight

419.39

Formula

C19H21N3O8
CAS No.
SMILES

O=C(COCCOCCNC1=CC=CC(C(N2C3C(NC(CC3)=O)=O)=O)=C1C2=O)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro: 

DMSO : 350 mg/mL (834.55 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3844 mL 11.9221 mL 23.8442 mL
5 mM 0.4769 mL 2.3844 mL 4.7688 mL
View the Complete Stock Solution Preparation Table

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

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Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.3844 mL 11.9221 mL 23.8442 mL 59.6104 mL
5 mM 0.4769 mL 2.3844 mL 4.7688 mL 11.9221 mL
10 mM 0.2384 mL 1.1922 mL 2.3844 mL 5.9610 mL
15 mM 0.1590 mL 0.7948 mL 1.5896 mL 3.9740 mL
20 mM 0.1192 mL 0.5961 mL 1.1922 mL 2.9805 mL
25 mM 0.0954 mL 0.4769 mL 0.9538 mL 2.3844 mL
30 mM 0.0795 mL 0.3974 mL 0.7948 mL 1.9870 mL
40 mM 0.0596 mL 0.2981 mL 0.5961 mL 1.4903 mL
50 mM 0.0477 mL 0.2384 mL 0.4769 mL 1.1922 mL
60 mM 0.0397 mL 0.1987 mL 0.3974 mL 0.9935 mL
80 mM 0.0298 mL 0.1490 mL 0.2981 mL 0.7451 mL
100 mM 0.0238 mL 0.1192 mL 0.2384 mL 0.5961 mL
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Pomalidomide-PEG2-acetic acid Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pomalidomide-PEG2-acetic acid2143097-05-4Pomalidomide-PEG2-CH2COOHE3 Ligase Ligand-Linker ConjugatesInhibitorinhibitorinhibit

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