2. Metabolic Enzyme/Protease
  3. Phosphatase
  4. PRL-3 Inhibitor I

PRL-3 Inhibitor I is a potent PRL-3 inhibitor with an IC50 of 0.9 μM. PRL-3 Inhibitor I shows a reduced invasion in cell-based assay.

For research use only. We do not sell to patients.

PRL-3 Inhibitor I Chemical Structure

PRL-3 Inhibitor I Chemical Structure

CAS No. : 893449-38-2

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 73 In-stock
Solution
10 mM * 1 mL in DMSO USD 73 In-stock
Solid
5 mg USD 66 In-stock
10 mg USD 110 In-stock
25 mg USD 220 In-stock
50 mg USD 330 In-stock
100 mg USD 495 In-stock
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

PRL-3 Inhibitor I Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

PRL-3 Inhibitor I is a potent PRL-3 inhibitor with an IC50 of 0.9 μM. PRL-3 Inhibitor I shows a reduced invasion in cell-based assay[1].

IC50 & Target

IC50: 0.9 μM (PRL-3)[1]
Cellular Effect
Cell Line Type Value Description References
DLD-1 IC50
7 μM
Compound: BR-1
Antimigratory activity against human DLD1 cells overexpressing PRL3 by crystal violet staining-based light microscopic analysis
Antimigratory activity against human DLD1 cells overexpressing PRL3 by crystal violet staining-based light microscopic analysis
[PMID: 23726031]
In Vitro

PRL-3 Inhibitor I (compound 5e) reduces the invasion of mouse melanoma B16F10 cells in a cell-based assay[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

PRL-3 Inhibitor I Related Antibodies
Molecular Weight

485.21

Formula

C17H11Br2NO2S2
CAS No.
Appearance

Solid

Color

Light yellow to green yellow

SMILES

O=C1NC(S/C1=C/C2=CC(Br)=CC=C2OCC3=CC=CC=C3Br)=S
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 41.67 mg/mL (85.88 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : 1 mg/mL (2.06 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0610 mL 10.3048 mL 20.6096 mL
5 mM 0.4122 mL 2.0610 mL 4.1219 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO 1 mM 2.0610 mL 10.3048 mL 20.6096 mL 51.5241 mL
DMSO 5 mM 0.4122 mL 2.0610 mL 4.1219 mL 10.3048 mL
10 mM 0.2061 mL 1.0305 mL 2.0610 mL 5.1524 mL
15 mM 0.1374 mL 0.6870 mL 1.3740 mL 3.4349 mL
20 mM 0.1030 mL 0.5152 mL 1.0305 mL 2.5762 mL
25 mM 0.0824 mL 0.4122 mL 0.8244 mL 2.0610 mL
30 mM 0.0687 mL 0.3435 mL 0.6870 mL 1.7175 mL
40 mM 0.0515 mL 0.2576 mL 0.5152 mL 1.2881 mL
50 mM 0.0412 mL 0.2061 mL 0.4122 mL 1.0305 mL
60 mM 0.0343 mL 0.1717 mL 0.3435 mL 0.8587 mL
80 mM 0.0258 mL 0.1288 mL 0.2576 mL 0.6441 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

PRL-3 Inhibitor I Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PRL-3 Inhibitor I893449-38-2PhosphataseinvasionmelanomaB16F10cellsInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
PRL-3 Inhibitor I
Cat. No.:
HY-112476
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

SAFETY DATA SHEET (SDS)

English - EN (537 KB) Français - FR (537 KB) Deutsch - DE (537 KB) Norwegian - NO (537 KB) Español - ES (537 KB) Swedish - SV (537 KB)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.