2. Metabolic Enzyme/Protease Neuronal Signaling Apoptosis Cell Cycle/DNA Damage Epigenetics
  3. Cytochrome P450 Monoamine Oxidase Bcl-2 Family Survivin PARP
  4. Proadifen hydrochloride (Standard)

Proadifen hydrochloride (Standard) 

Cat. No.: HY-B1311R Purity: ≥98%
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Proadifen (hydrochloride) (Standard) is the analytical standard of Proadifen (hydrochloride). This product is intended for research and analytical applications. Proadifen (SKF-525A) hydrochloride is a non-competitive Cytochrome P450 inhibitor with an IC50 value of 19 μM. Proadifen hydrochloride reduces monoamine oxidase A (MAO-A) activity and reverses the antidepressantlike behavioral effect of Imipramine (HY-B1490A) and Desipramine (HY-B1272A) in rats. Proadifen hydrochloride also reduces N, N-dimethyltryptamine (DMT) metabolism in liver microsomes and inhibits N-demethylationand Acridone (HY-W007771) formation. Proadifen hydrochloride augments Lipopolysaccharide (LPS) (HY-D1056)-induced fever and exacerbates Prostaglandin E2 (PGE2) (HY-101952) levels in the rat. Proadifen hydrochloride is promising for research of metabolism-related deseases, ovarian carcinoma, inflammation and dopamine neurons-related deseases[4].

For research use only. We do not sell to patients.

Proadifen hydrochloride (Standard) Chemical Structure

Proadifen hydrochloride (Standard) Chemical Structure

CAS No. : 62-68-0

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Description

Proadifen (hydrochloride) (Standard) is the analytical standard of Proadifen (hydrochloride). This product is intended for research and analytical applications. Proadifen (SKF-525A) hydrochloride is a non-competitive Cytochrome P450 inhibitor with an IC50 value of 19 μM. Proadifen hydrochloride reduces monoamine oxidase A (MAO-A) activity and reverses the antidepressantlike behavioral effect of Imipramine (HY-B1490A) and Desipramine (HY-B1272A) in rats. Proadifen hydrochloride also reduces N, N-dimethyltryptamine (DMT) metabolism in liver microsomes and inhibits N-demethylationand Acridone (HY-W007771) formation. Proadifen hydrochloride augments Lipopolysaccharide (LPS) (HY-D1056)-induced fever and exacerbates Prostaglandin E2 (PGE2) (HY-101952) levels in the rat. Proadifen hydrochloride is promising for research of metabolism-related deseases, ovarian carcinoma, inflammation and dopamine neurons-related deseases[4].

Molecular Weight

389.96

Formula

C23H32ClNO2
CAS No.
SMILES

O=C(OCCN(CC)CC)C(CCC)(C1=CC=CC=C1)C2=CC=CC=C2.[H]Cl
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
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Proadifen hydrochloride (Standard) Related Classifications

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Keywords:

Proadifen hydrochloride (Standard)62-68-0Cytochrome P450Monoamine OxidaseBcl-2 FamilySurvivinPARPCYPsMAOpoly ADP ribose polymeraseCytochrome P450 inhibitormonoamine oxidase AantidepressantDMTliver microsomesAcridoneprostaglandin E2ratayahuascainflammationovarian carcinomaInhibitorinhibitorinhibit

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