Progesterone-¹³C₃

Name: Progesterone- 13 C 3
Brand: MedChemExpress
SKU: HY-N0437S2
Rating: 4.5 (1 reviews)

Cat. No.: HY-N0437S2 Purity: 99.60%: FAQs
Data Sheet SDS COA Handling Instructions Technical Support

Progesterone-¹³C₃ is the ¹³C-labeled Progesterone. Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy.

For research use only. We do not sell to patients.

Progesterone-<sup>13</sup>C<sub>3</sub> Chemical Structure

Progesterone-¹³C₃ Chemical Structure

CAS No. : 327048-87-3

Size	Price	Stock	Quantity
5 mg		Get quote	Estimated Time of Arrival: December 31
1 mg		In-stock	Estimated Time of Arrival: December 31

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Progesterone-¹³C₃:

Progesterone In-stock

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Progesterone-¹³C₃ is the ¹³C-labeled Progesterone. Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

317.44

Formula

C₁₈¹³C₃H₃₀O₂

CAS No.

327048-87-3

Unlabeled CAS

57-83-0

Appearance

Solid

Color

White to off-white

SMILES

C[C@@]12[C@]3([H])[C@](CCC1=[13CH][13C]([13CH2]C2)=O)([H])[C@@]4([H])[C@](CC3)([C@H](CC4)C(C)=O)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 50 mg/mL (157.51 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.1502 mL	15.7510 mL	31.5020 mL
5 mM	0.6300 mL	3.1502 mL	6.3004 mL
10 mM	0.3150 mL	1.5751 mL	3.1502 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Concentration _(final)

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In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.60%

Select Batch:

Data Sheet (276 KB) SDS (419 KB)

COA (254 KB) RP-HPLC (280 KB) MS (247 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

[2]. Schindler AE, et al. Classification and pharmacology of progestins. Maturitas. 2003 Dec 10;46 Suppl 1:S7-S16. [Content Brief]

[3]. Zava DT, et al. Estrogen and progestin bioactivity of foods, herbs, and spices. Proc Soc Exp Biol Med. 1998 Mar;217(3):369-78. [Content Brief]

[4]. Komesaroff PA, et al. Effects of wild yam extract on menopausal symptoms, lipids and sex hormones in healthy menopausal women. Climacteric. 2001 Jun;4(2):144-50. [Content Brief]

[5]. Girling JE, et al. Progesterone, but not estrogen, stimulates vessel maturation in the mouse endometrium. Endocrinology. 2007 Nov;148(11):5433-41. Epub 2007 Aug 9. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.1502 mL	15.7510 mL	31.5020 mL	78.7550 mL
	5 mM	0.6300 mL	3.1502 mL	6.3004 mL	15.7510 mL
	10 mM	0.3150 mL	1.5751 mL	3.1502 mL	7.8755 mL
	15 mM	0.2100 mL	1.0501 mL	2.1001 mL	5.2503 mL
	20 mM	0.1575 mL	0.7876 mL	1.5751 mL	3.9378 mL
	25 mM	0.1260 mL	0.6300 mL	1.2601 mL	3.1502 mL
	30 mM	0.1050 mL	0.5250 mL	1.0501 mL	2.6252 mL
	40 mM	0.0788 mL	0.3938 mL	0.7876 mL	1.9689 mL
	50 mM	0.0630 mL	0.3150 mL	0.6300 mL	1.5751 mL
	60 mM	0.0525 mL	0.2625 mL	0.5250 mL	1.3126 mL
	80 mM	0.0394 mL	0.1969 mL	0.3938 mL	0.9844 mL
	100 mM	0.0315 mL	0.1575 mL	0.3150 mL	0.7876 mL