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PROT-IN-1 (Compound 2) is a proline transporter (PROT) inhibitor (IC50: 1.48 μM). PROT-IN-1 can be used for research of cognitive disorders.

For research use only. We do not sell to patients.

PROT-IN-1 Chemical Structure

PROT-IN-1 Chemical Structure

CAS No. : 329935-45-7

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5 mg USD 98 In-stock
10 mg USD 160 In-stock
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Based on 1 publication(s) in Google Scholar

PROT-IN-1 Related Antibodies

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Description

PROT-IN-1 (Compound 2) is a proline transporter (PROT) inhibitor (IC50: 1.48 μM). PROT-IN-1 can be used for research of cognitive disorders[1].

Molecular Weight

342.43

Formula

C23H22N2O
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(N1CCN(CC1)C2=CC=CC=C2)C3=CC=C(C4=CC=CC=C4)C=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (73.01 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9203 mL 14.6015 mL 29.2030 mL
5 mM 0.5841 mL 2.9203 mL 5.8406 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.9203 mL 14.6015 mL 29.2030 mL 73.0076 mL
5 mM 0.5841 mL 2.9203 mL 5.8406 mL 14.6015 mL
10 mM 0.2920 mL 1.4602 mL 2.9203 mL 7.3008 mL
15 mM 0.1947 mL 0.9734 mL 1.9469 mL 4.8672 mL
20 mM 0.1460 mL 0.7301 mL 1.4602 mL 3.6504 mL
25 mM 0.1168 mL 0.5841 mL 1.1681 mL 2.9203 mL
30 mM 0.0973 mL 0.4867 mL 0.9734 mL 2.4336 mL
40 mM 0.0730 mL 0.3650 mL 0.7301 mL 1.8252 mL
50 mM 0.0584 mL 0.2920 mL 0.5841 mL 1.4602 mL
60 mM 0.0487 mL 0.2434 mL 0.4867 mL 1.2168 mL
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PROT-IN-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PROT-IN-1329935-45-7OthersAlzheimer’s diseaseDimentiaproline transportercognition improvementInhibitorinhibitorinhibit

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