2. Recombinant Proteins
  3. Cytokines and Growth Factors
  4. Interleukin & Receptors
  5. IL-15 Receptor

IL-15 Receptor

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IL-15 Receptor (IL-15R) is a heterotrimeric receptor which consists of IL-15Rα, IL-2Rβ and IL-2Rγc. IL-15R binds IL-15 (structurally similar to IL-2). IL-15Rα is a high affinity receptor for IL-15 (Kd: 100 pM), and IL-15R shares IL-2Rβ and IL-2Rγc subunits with IL-2R[1]. IL-15Rα can bind IL-15 and thereby activating the antitumor functions of NK cells and CD8+ T cells[2]. IL-15R alpha plays an important role in memory CD8 T cell homeostasis and lymphocyte development[1]. IL-15R alpha is also required for transporting of IL-15 from the endoplasmic reticulum to the cell surface[3].IL-15Rα is expressed on lymphocytes, myeloid cells, nonlymphoid and nonhematopoietic cells[1].

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Cat. No. Product Name / Synonyms Species Source
  • HY-P70655
    IL-15R alpha & IL-15 Fusion Protein, Human (HEK293, Fc)

    IL15RA& IL15; Interleukin-15; IL-15; IL15; IL-15 receptor subunit alpha; IL-15RA; IL-15R-alpha; interleukin-15 receptor subunit alpha

    		Human HEK293
    IL-15R alpha is a high affinity receptor for IL-15 (Kd: 100 pM). IL-15 is essential for the development and function natural killer (NK) cell, NKT cell and memory (m) CD8+ T cell. IL-15R alpha maintains memory CD8+ T cell homeostasis and lymphocyte development. IL-15R alpha/IL-15 complex can activate the antitumor functions of NK cells and CD8+ T cells. IL-15R alpha & IL-15 Fusion Protein, Human (HEK293, Fc) is a recombinant human IL-15R alpha (I31-D96) & IL-15 (N49-S162) fusion protein with a C-Terminal hFc tag, which is produced in HEK293 cells.
  • HY-P77699
    IL-15R alpha & IL-15 Protein, Human (HEK293, His)

    IL-15 R alpha; CD215; IL15RA; IL-15RA; IL-15R-alpha1; Interleukin-15; IL-15; IL15

    		Human HEK293
    IL-15R alpha is a high affinity receptor for IL-15 (Kd: 100 pM). IL-15 is essential for the development and function natural killer (NK) cell, NKT cell and memory (m) CD8+ T cell. IL-15R alpha maintains memory CD8+ T cell homeostasis and lymphocyte development. IL-15R alpha/IL-15 complex can activate the antitumor functions of NK cells and CD8+ T cells. IL-15R alpha & IL-15 Protein, Human (HEK293, His) is a recombinant human IL-15R alpha (I31-S108) & IL-15 (N49-S162) fusion protein with a C-Terminal His tag, which is produced in HEK293 cells.
  • HY-P78154
    IL-15R alpha Protein, Human (Biotinylated, HEK293, His-Avi)

    IL-15 R alpha; CD215; IL-15RA; MGC104179

    		Human HEK293
    IL-15R alpha is a high affinity receptor for IL-15 (Kd: 100 pM). IL-15R alpha binds IL-15 and thereby activating the antitumor functions of NK cells and CD8+ T cells. IL-15R alpha plays an important role in memory CD8+ T cell homeostasis and lymphocyte development. IL-15R alpha Protein, Human (Biotinylated, HEK293, His-Avi) is a biotinylated recombinant human extracellular region of IL-15R alpha (I31-T205) with a C-Terminal His-Avi tag, which is produced in HEK293 cells.
  • HY-P71978
    IL-15R alpha Protein, Mouse (HEK293, hFc)

    Il15ra; Interleukin-15 receptor subunit alpha; IL-15 receptor subunit alpha; IL-15R-alpha; IL-15RA; CD antigen CD215; Soluble interleukin-15 receptor subunit alpha; sIL-15 receptor subunit alpha; sIL-15R-alpha; sIL-15RA;

    		Mouse HEK293
    IL-15R alpha is a high affinity receptor for IL-15 (Kd: 100 pM). IL-15R alpha binds IL-15 and thereby activating the antitumor functions of NK cells and CD8+ T cells. IL-15R alpha plays an important role in memory CD8+ T cell homeostasis and lymphocyte development. IL-15R alpha Protein, Mouse (HEK293, hFc) is a recombinant mouse extracellular region of IL-15R alpha (G33-K205) with a C-Terminal hFc tag, which is produced in HEK293 cells.
  • HY-P78558
    IL-15R alpha & IL-15 Protein, Mouse (HEK293, His)

    IL-15 R alpha; CD215; IL15RA; IL-15RA; IL-15R-alpha1; Interleukin-15; IL-15; IL15

    		Mouse HEK293
    IL-15R alpha Protein, the high-affinity receptor for interleukin-15, crucially signals in cis and trans, presenting IL-15 to neighboring IL2RG-expressing cells. In neutrophils, it activates SYK kinase, essential for IL-15-induced phagocytosis in a SYK-dependent manner. IL-15R alpha forms a heterotrimer with IL2RB and IL2RG, capable of self-association. Interactions with SYK underscore its intricate involvement in cellular signaling pathways. IL-15R alpha & IL-15 Protein, Mouse (HEK293, His) is a recombinant protein dimer complex containing mouse-derived IL-15R alpha & IL-15 protein, expressed by HEK293 , with C-His labeled tag. IL-15R alpha & IL-15 Protein, Mouse (HEK293, His), has molecular weight of ~36 kDa.
  • HY-P77700
    IL-15R alpha & IL-15 Protein, Human (Biotinylated, HEK293, His)

    IL-15 R alpha; CD215; IL15RA; IL-15RA; IL-15R-alpha1; Interleukin-15; IL-15; IL15

    		Human HEK293
    IL-15R alpha is a high affinity receptor for IL-15 (Kd: 100 pM). IL-15 is essential for the development and function natural killer (NK) cell, NKT cell and memory (m) CD8+ T cell. IL-15R alpha maintains memory CD8+ T cell homeostasis and lymphocyte development. IL-15R alpha/IL-15 complex can activate the antitumor functions of NK cells and CD8+ T cells. IL-15R alpha & IL-15 Protein, Human (Biotinylated, HEK293, His) is a recombinant biotinylated human IL-15R alpha (I31-S108) & IL-15 (N49-S162) fusion protein with a C-Terminal His tag, which is produced in HEK293 cells.
  • HY-P78468
    IL-15R alpha Protein, Human (HEK293, His-Avi)

    IL-15 R alpha; CD215; IL-15RA; MGC104179

    		Human HEK293
    IL-15R alpha is a high affinity receptor for IL-15 (Kd: 100 pM). IL-15R alpha binds IL-15 and thereby activating the antitumor functions of NK cells and CD8+ T cells. IL-15R alpha plays an important role in memory CD8+ T cell homeostasis and lymphocyte development. IL-15R alpha Protein, Human (HEK293, His-Avi) is a recombinant human extracellular region of IL-15R alpha (I31-T205) with a C-Terminal His-Avi tag, which is produced in HEK293 cells.
  • HY-P701298
    FITC-Labeled IL-15R alpha Protein, Human (HEK293, Fc)

    IL-15 R alpha; CD215; IL15RA; IL-15RA; IL-15R-alpha

    		Human HEK293
    IL-15R alpha Protein, a proven high-affinity receptor for interleukin-15, signals in both cis and trans. In neutrophils, it activates SYK kinase, crucial for IL-15-induced phagocytosis in a SYK-dependent manner. Different isoforms may introduce variations in signal transduction. Notably, IL-15R alpha Protein, while having high affinity, does not directly bind to IL15. FITC-Labeled IL-15R alpha Protein, Human (HEK293, Fc) is the recombinant human-derived FITC-Labeled IL-15R alpha protein, expressed by HEK293 , with Fc labeled tag.
  • HY-P701299
    PE-Labeled IL-15R alpha Protein, Human (HEK293, Fc)

    IL-15 R alpha; CD215; IL15RA; IL-15RA; IL-15R-alpha

    		Human HEK293
    IL-15R alpha Protein, a proven high-affinity receptor for interleukin-15, signals in both cis and trans. In neutrophils, it activates SYK kinase, crucial for IL-15-induced phagocytosis in a SYK-dependent manner. Different isoforms may introduce variations in signal transduction. Notably, IL-15R alpha Protein, while having high affinity, does not directly bind to IL15. PE-Labeled IL-15R alpha Protein, Human (HEK293, Fc) is the recombinant human-derived PE-Labeled IL-15R alpha protein, expressed by HEK293 , with Fc labeled tag.
  • HY-P72592
    IL-15R alpha Protein, Human (142a.a, HEK293, Fc)

    Interleukin-15 receptor subunit alpha; IL-15R-alpha; IL-15RA; CD215; sIL-15R-alpha; sIL-15RA

    		Human HEK293
    IL-15R alpha is a high affinity receptor for IL-15 (Kd: 100 pM). IL-15R alpha binds IL-15 and thereby activating the antitumor functions of NK cells and CD8+ T cells. IL-15R alpha plays an important role in memory CD8+ T cell homeostasis and lymphocyte development. IL-15R alpha Protein, Human (142a.a, HEK293, Fc) is a recombinant human extracellular region of IL-15R alpha (I31-T172) with a C-Terminal Fc tag, which is produced in HEK293 cells.
Cat. No. Product Name Effect Purity