2. Antibody-drug Conjugate/ADC Related
  3. Radionuclide-Drug Conjugates (RDCs)
  4. PSMA-BCH

PSMA-BCH  (Synonyms: NOTA-PSMA)

Cat. No.: HY-155483 Purity: 99.93%
SDS COA Handling Instructions

Molarity Calculator

PSMA-BCH (NOTA-PSMA) is a NOTA-conjugated precursor. NOTA is a bifunctional chelate which acts as the framework to construct PET imaging tools.

For research use only. We do not sell to patients.

PSMA-BCH Chemical Structure

PSMA-BCH Chemical Structure

CAS No. : 1703768-73-3

Size Price Stock Quantity
5 mg USD 410 In-stock
10 mg USD 650 In-stock
50 mg   Get quote  
100 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

PSMA-BCH Related Antibodies

Top Publications Citing Use of Products

View All Radionuclide-Drug Conjugates (RDCs) Isoform Specific Products:

View All Isoforms
RDC Peptide RDC Antibody RDC Bifunctional Chelator RDC Linker Other

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

PSMA-BCH (NOTA-PSMA) is a NOTA-conjugated precursor. NOTA is a bifunctional chelate which acts as the framework to construct PET imaging tools[1].

IC50 & Target

RDC Bifunctional Chelator

 

Molecular Weight

941.03

Formula

C45H64N8O14
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C([C@@H]1CC[C@H](CC1)CNC(CN2CCN(CCN(CC2)CC(O)=O)CC(O)=O)=O)N[C@H](C(NCCCC[C@@H](C(O)=O)NC(N[C@H](C(O)=O)CCC(O)=O)=O)=O)CC3=CC4=C(C=CC=C4)C=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (132.83 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.0627 mL 5.3133 mL 10.6267 mL
5 mM 0.2125 mL 1.0627 mL 2.1253 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.0627 mL 5.3133 mL 10.6267 mL 26.5666 mL
5 mM 0.2125 mL 1.0627 mL 2.1253 mL 5.3133 mL
10 mM 0.1063 mL 0.5313 mL 1.0627 mL 2.6567 mL
15 mM 0.0708 mL 0.3542 mL 0.7084 mL 1.7711 mL
20 mM 0.0531 mL 0.2657 mL 0.5313 mL 1.3283 mL
25 mM 0.0425 mL 0.2125 mL 0.4251 mL 1.0627 mL
30 mM 0.0354 mL 0.1771 mL 0.3542 mL 0.8856 mL
40 mM 0.0266 mL 0.1328 mL 0.2657 mL 0.6642 mL
50 mM 0.0213 mL 0.1063 mL 0.2125 mL 0.5313 mL
60 mM 0.0177 mL 0.0886 mL 0.1771 mL 0.4428 mL
80 mM 0.0133 mL 0.0664 mL 0.1328 mL 0.3321 mL
100 mM 0.0106 mL 0.0531 mL 0.1063 mL 0.2657 mL
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

PSMA-BCH Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PSMA-BCH1703768-73-3NOTA-PSMARadionuclide-Drug Conjugates (RDCs)NOTAbifunctional chelateframeworkPETInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
PSMA-BCH
Cat. No.:
HY-155483
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

SAFETY DATA SHEET (SDS)

English - EN (251 KB) Français - FR (251 KB) Deutsch - DE (251 KB) Norwegian - NO (251 KB) Español - ES (251 KB) Swedish - SV (251 KB)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.