2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Purine nucleoside phosphorylase, Microorganism

Purine nucleoside phosphorylase, Microorganism  (Synonyms: PNP)

Cat. No.: HY-P2724
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Purine nucleoside phosphorylase, Microorganism (PNP) is a key enzyme in purine metabolism, which is involved in the purine rescue pathway. The deficiency of Purine nucleoside phosphorylase resulted in impaired T cell function. In the presence of inorganic orthophosphate as the second substrate, Purine nucleoside phosphorylase catalyzes the breaking of the glycosidic bond between ribose and deoxyribonucleoside to generate purine base and ribose (deoxyribose) -1-phosphate.

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Purine nucleoside phosphorylase, Microorganism Chemical Structure

Purine nucleoside phosphorylase, Microorganism Chemical Structure

CAS No. : 9030-21-1

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Description

Purine nucleoside phosphorylase, Microorganism (PNP) is a key enzyme in purine metabolism, which is involved in the purine rescue pathway. The deficiency of Purine nucleoside phosphorylase resulted in impaired T cell function. In the presence of inorganic orthophosphate as the second substrate, Purine nucleoside phosphorylase catalyzes the breaking of the glycosidic bond between ribose and deoxyribonucleoside to generate purine base and ribose (deoxyribose) -1-phosphate[1].

In Vitro

Product Information
Molecular weight: about 100 kDa, trimer
pH stability: 6.0-9.0, optimum pH 6.5-8.0
Inhibitors: p-Chloromercuric benzoic acid, SDS, Hg2+, Ag+

Instructions
Soluble in water (below 100 mg/mL concentration), or dissolved in buffer according to specific experimental references.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Appearance

Solid

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White to off-white

SMILES

[Purine nucleoside phosphorylase, Microorganism]
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro: 

H2O : ≥ 100 mg/mL

*"≥" means soluble, but saturation unknown.

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Purity & Documentation

Data Sheet (263 KB) SDS (251 KB)

COA (242 KB)

Handling Instructions (2659 KB)
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Purine nucleoside phosphorylase, Microorganism Related Classifications

Keywords:

Purine nucleoside phosphorylase, Microorganism9030-21-1PNPEndogenous MetaboliteInhibitorinhibitorinhibit

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