2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Purine nucleoside phosphorylase, Microorganism

Purine nucleoside phosphorylase, Microorganism  (Synonyms: PNP)

Cat. No.: HY-P2724
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Purine nucleoside phosphorylase, Microorganism (PNP) is a key enzyme in purine metabolism, which is involved in the purine rescue pathway. The deficiency of Purine nucleoside phosphorylase resulted in impaired T cell function. In the presence of inorganic orthophosphate as the second substrate, Purine nucleoside phosphorylase catalyzes the breaking of the glycosidic bond between ribose and deoxyribonucleoside to generate purine base and ribose (deoxyribose) -1-phosphate.

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Purine nucleoside phosphorylase, Microorganism Chemical Structure

Purine nucleoside phosphorylase, Microorganism Chemical Structure

CAS No. : 9030-21-1

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Purine nucleoside phosphorylase, Microorganism Related Antibodies

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Description

Purine nucleoside phosphorylase, Microorganism (PNP) is a key enzyme in purine metabolism, which is involved in the purine rescue pathway. The deficiency of Purine nucleoside phosphorylase resulted in impaired T cell function. In the presence of inorganic orthophosphate as the second substrate, Purine nucleoside phosphorylase catalyzes the breaking of the glycosidic bond between ribose and deoxyribonucleoside to generate purine base and ribose (deoxyribose) -1-phosphate[1].

In Vitro

Product Information
Molecular weight: about 100 kDa, trimer
pH stability: 6.0-9.0, optimum pH 6.5-8.0
Inhibitors: p-Chloromercuric benzoic acid, SDS, Hg2+, Ag+

Instructions
Soluble in water (below 100 mg/mL concentration), or dissolved in buffer according to specific experimental references.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Purine nucleoside phosphorylase, Microorganism Related Antibodies
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[Purine nucleoside phosphorylase, Microorganism]
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H2O : ≥ 100 mg/mL

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Purine nucleoside phosphorylase, Microorganism Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Purine nucleoside phosphorylase, Microorganism9030-21-1PNPEndogenous MetaboliteInhibitorinhibitorinhibit

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