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  3. (R)-INCB054329

(R)-INCB054329 is the isomer of INCB054329 (HY-112504), and can be used as an experimental control. INCB054329 is a potent BET inhibitor.

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(R)-INCB054329 Chemical Structure

(R)-INCB054329 Chemical Structure

CAS No. : 1628607-63-5

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5 mg USD 650 In-stock
10 mg USD 980 In-stock
25 mg USD 1750 In-stock
50 mg USD 2600 In-stock
100 mg USD 4100 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of (R)-INCB054329:

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Description

(R)-INCB054329 is the isomer of INCB054329 (HY-112504), and can be used as an experimental control. INCB054329 is a potent BET inhibitor.

Molecular Weight

348.36

Formula

C19H16N4O3

CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C1NC2=C3N1[C@H](C4=NC=CC=C4)COC3=C(C5=C(C)ON=C5C)C=C2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (287.06 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.8706 mL 14.3530 mL 28.7059 mL
5 mM 0.5741 mL 2.8706 mL 5.7412 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.8706 mL 14.3530 mL 28.7059 mL 71.7648 mL
5 mM 0.5741 mL 2.8706 mL 5.7412 mL 14.3530 mL
10 mM 0.2871 mL 1.4353 mL 2.8706 mL 7.1765 mL
15 mM 0.1914 mL 0.9569 mL 1.9137 mL 4.7843 mL
20 mM 0.1435 mL 0.7176 mL 1.4353 mL 3.5882 mL
25 mM 0.1148 mL 0.5741 mL 1.1482 mL 2.8706 mL
30 mM 0.0957 mL 0.4784 mL 0.9569 mL 2.3922 mL
40 mM 0.0718 mL 0.3588 mL 0.7176 mL 1.7941 mL
50 mM 0.0574 mL 0.2871 mL 0.5741 mL 1.4353 mL
60 mM 0.0478 mL 0.2392 mL 0.4784 mL 1.1961 mL
80 mM 0.0359 mL 0.1794 mL 0.3588 mL 0.8971 mL
100 mM 0.0287 mL 0.1435 mL 0.2871 mL 0.7176 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
(R)-INCB054329
Cat. No.:
HY-112504D
Quantity:
MCE Japan Authorized Agent: