2. GPCR/G Protein Immunology/Inflammation
  3. CXCR
  4. (Rac)-SCH 563705

(Rac)-SCH 563705 is a racemic mixture of SCH 563705 (HY-10011). SCH 563705 (compound 16) is a potent and orally active CXCR2 and CXCR1 antagonist with IC50 values ​​of 1.3 nM and 7.3 nM and Ki values ​​of 1 nM and 3 nM, respectively.

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(Rac)-SCH 563705 Chemical Structure

(Rac)-SCH 563705 Chemical Structure

CAS No. : 2701435-64-3

Size Price Stock Quantity
5 mg USD 440 In-stock
10 mg USD 682 In-stock
25 mg USD 1296 In-stock
50 mg USD 1880 In-stock
100 mg USD 2700 In-stock
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500 mg   Get quote  

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Other Forms of (Rac)-SCH 563705:

(Rac)-SCH 563705 Related Antibodies

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Description

(Rac)-SCH 563705 is a racemic mixture of SCH 563705 (HY-10011). SCH 563705 (compound 16) is a potent and orally active CXCR2 and CXCR1 antagonist with IC50 values ​​of 1.3 nM and 7.3 nM and Ki values ​​of 1 nM and 3 nM, respectively[1][2].

Molecular Weight

425.48

Formula

C23H27N3O5
CAS No.
SMILES

O=C(C(NC1=CC=CC(C(N(C)C)=O)=C1O)=C2NC(CC)C3=CC(C(C)C)=CO3)C2=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro: 

DMSO : 200 mg/mL (470.06 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3503 mL 11.7514 mL 23.5029 mL
5 mM 0.4701 mL 2.3503 mL 4.7006 mL
View the Complete Stock Solution Preparation Table

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Purity & Documentation
References

Complete Stock Solution Preparation Table

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.3503 mL 11.7514 mL 23.5029 mL 58.7572 mL
5 mM 0.4701 mL 2.3503 mL 4.7006 mL 11.7514 mL
10 mM 0.2350 mL 1.1751 mL 2.3503 mL 5.8757 mL
15 mM 0.1567 mL 0.7834 mL 1.5669 mL 3.9171 mL
20 mM 0.1175 mL 0.5876 mL 1.1751 mL 2.9379 mL
25 mM 0.0940 mL 0.4701 mL 0.9401 mL 2.3503 mL
30 mM 0.0783 mL 0.3917 mL 0.7834 mL 1.9586 mL
40 mM 0.0588 mL 0.2938 mL 0.5876 mL 1.4689 mL
50 mM 0.0470 mL 0.2350 mL 0.4701 mL 1.1751 mL
60 mM 0.0392 mL 0.1959 mL 0.3917 mL 0.9793 mL
80 mM 0.0294 mL 0.1469 mL 0.2938 mL 0.7345 mL
100 mM 0.0235 mL 0.1175 mL 0.2350 mL 0.5876 mL
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(Rac)-SCH 563705 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(Rac)-SCH 5637052701435-64-3CXCRCXC chemokine receptorsC-X-C motif chemokine receptorsRacemic mixturesorally activeantagonistsInhibitorinhibitorinhibit

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