BOLA1 Protein, Human (His)

BOLA1 Protein plays a vital role in assembling mitochondrial iron-sulfur (Fe-S) clusters, facilitating their insertion into specific mitochondrial proteins. It likely collaborates with monothiol glutaredoxin GLRX5 in this process, emphasizing its role in mitochondrial Fe-S cluster biogenesis. Additionally, BOLA1 may contribute to cellular defense against oxidative stress, highlighting potential connections between mitochondrial iron homeostasis and responses to oxidative challenges. BOLA1 Protein, Human (His) is the recombinant human-derived BOLA1 protein, expressed by E. coli, with N-His labeled tag. The total length of BOLA1 Protein, Human (His) is 137 a.a., with molecular weight of ~10 kDa.

BOLA1 Protein functions as a crucial factor in the assembly of mitochondrial iron-sulfur (Fe-S) clusters, aiding in the insertion of these clusters into specific mitochondrial proteins. It likely collaborates with the monothiol glutaredoxin GLRX5 in this process, emphasizing its role in mitochondrial Fe-S cluster biogenesis. Additionally, BOLA1 may contribute to cellular defense against oxidative stress. Its interaction with GLRX5 further underscores its involvement in intricate molecular mechanisms, highlighting potential connections between mitochondrial iron homeostasis and cellular responses to oxidative challenges.

Human

E. coli

N-His

Q9Y3E2 (M1-P137)

51027  [NCBI]

Approximately 10 kDa

Greater than 90% as determined by reducing SDS-PAGE

<1 EU/μg, determined by LAL method.