E-Selectin/CD62E Protein, Mouse (HEK293, Fc)

E-Selectin/CD62E protein, a cell-surface glycoprotein, mediates the adhesion of blood neutrophils to cytokine-activated endothelium through interaction with SELPLG/PSGL1. It also potentially contributes to capillary morphogenesis and interacts with SELPLG/PSGL1 and PODXL2. These multifaceted interactions highlight E-Selectin's role in cell adhesion and its potential influence on vascular development. E-Selectin/CD62E Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived E-Selectin/CD62E protein, expressed by HEK293 , with C-hFc labeled tag.

E-Selectin/CD62E protein, a cell-surface glycoprotein, plays a crucial role in immunoadhesion by mediating the adhesion of blood neutrophils to cytokine-activated endothelium through interaction with SELPLG/PSGL1. Beyond its involvement in immune responses, E-Selectin may also contribute to capillary morphogenesis. The protein interacts with SELPLG/PSGL1 and PODXL2 through the sialyl Lewis X epitope, with SELPLG sulfation seemingly not required for this interaction. These interactions highlight the multifaceted roles of E-Selectin in mediating cell adhesion events and potentially influencing processes related to vascular development.

Mouse

HEK293

C-hFc

NP_035475.1 (W22-P557)

20339  [NCBI]

Approximately 101 kDa

Greater than 90% as determined by reducing SDS-PAGE

<1 EU/μg, determined by LAL method.