ICAM-5 Protein, Human (132a.a, HEK293, Fc)

The ICAM-5 protein functions as a ligand for the leukocyte adhesion protein LFA-1 (integrin α-L/β-2) and mediates the cell adhesion process. As a member of the ICAM family, ICAM-5 interacts with LFA-1 and is critical for immune cell adhesion and communication. ICAM-5 Protein, Human (132a.a, HEK293, Fc) is the recombinant human-derived ICAM-5 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of ICAM-5 Protein, Human (132a.a, HEK293, Fc) is 101 a.a., with molecular weight of ~38.6 kDa.

ICAM-5 Protein serves as a ligand for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2), indicating its role in mediating cellular adhesion processes. As a member of the ICAM protein family, ICAM-5 is implicated in interactions with LFA-1, which is crucial for the adhesion and communication between immune cells. This interaction likely plays a role in immune responses and cellular trafficking, contributing to the dynamic regulation of immune cell activities. The engagement of ICAM-5 with LFA-1 underscores its importance in the intricate network of adhesion molecules that modulate immune cell interactions and functions.

Human

HEK293

C-hFc

Q9UMF0 (E32-Q132)

7087  [NCBI]

Approximately 38.6 kDa

Greater than 85% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.