1. Recombinant Proteins
  2. Receptor Proteins
  3. Cell Adhesion Molecules (CAMs)
  4. Immunoglobulin-like Cell Adhesion Molecules
  5. Intercellular Adhesion Molecule 5 (ICAM-5)
  6. ICAM-5 Protein, Human (539a.a, HEK293, Fc)

ICAM-5 Protein, Human (539a.a, HEK293, Fc)

Cat. No.: HY-P74870
Handling Instructions

The ICAM-5 protein functions as a ligand for the leukocyte adhesion protein LFA-1 (integrin α-L/β-2) and mediates the cell adhesion process. As a member of the ICAM family, ICAM-5 interacts with LFA-1 and is critical for immune cell adhesion and communication. ICAM-5 Protein, Human (539a.a, HEK293, Fc) is the recombinant human-derived ICAM-5 protein, expressed by HEK293 , with C-hFc labeled tag.

For research use only. We do not sell to patients.

Surface Plasmon Resonance (SPR) Assay Service   Protein Expression Service

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  • Biological Activity

  • Technical Parameters

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Description

The ICAM-5 protein functions as a ligand for the leukocyte adhesion protein LFA-1 (integrin α-L/β-2) and mediates the cell adhesion process. As a member of the ICAM family, ICAM-5 interacts with LFA-1 and is critical for immune cell adhesion and communication. ICAM-5 Protein, Human (539a.a, HEK293, Fc) is the recombinant human-derived ICAM-5 protein, expressed by HEK293 , with C-hFc labeled tag.

Background

ICAM-5 Protein serves as a ligand for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2), indicating its role in mediating cellular adhesion processes. As a member of the ICAM protein family, ICAM-5 is implicated in interactions with LFA-1, which is crucial for the adhesion and communication between immune cells. This interaction likely plays a role in immune responses and cellular trafficking, contributing to the dynamic regulation of immune cell activities. The engagement of ICAM-5 with LFA-1 underscores its importance in the intricate network of adhesion molecules that modulate immune cell interactions and functions.

Species

Human

Source

HEK293

Tag

C-hFc

Accession

Q9UMF0 (E32-E570)

Gene ID
Synonyms
ICAM5; Intercellular Adhesion Molecule 5; Telencephalin; TLCNTelencephalin
Molecular Weight

Approximately 84.9 kDa

Purity

Greater than 90% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
ICAM-5 Protein, Human (539a.a, HEK293, Fc)
Cat. No.:
HY-P74870
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