1. Recombinant Proteins
  2. Enzymes & Regulators
  3. Transferases (EC 2)
  4. PRRG2 Protein, Human (HEK293, Fc)

PRRG2 Protein, Human (HEK293, Fc)

Cat. No.: HY-P77157
COA Handling Instructions

PRRG2 protein interacts with NEDD4, suggesting a role in cellular regulation. In addition, it associates with the transcriptional coactivator YAP1, suggesting a possible involvement in transcriptional regulation. PRRG2 Protein, Human (HEK293, Fc) is the recombinant human-derived PRRG2 protein, expressed by HEK293 , with C-mFc labeled tag.

For research use only. We do not sell to patients.

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5 μg $55 In-stock
10 μg $85 In-stock
50 μg $215 In-stock
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  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

PRRG2 protein interacts with NEDD4, suggesting a role in cellular regulation. In addition, it associates with the transcriptional coactivator YAP1, suggesting a possible involvement in transcriptional regulation. PRRG2 Protein, Human (HEK293, Fc) is the recombinant human-derived PRRG2 protein, expressed by HEK293 , with C-mFc labeled tag.

Background

The PRRG2 protein exhibits specific molecular interactions, including its association with NEDD4, indicating a potential role in cellular regulatory processes. Moreover, PRRG2 interacts with the transcriptional coactivator YAP1 via its cytoplasmic domain, suggesting a possible involvement in modulating transcriptional activities. These interactions highlight the intricate nature of PRRG2 and imply its participation in diverse cellular functions and signaling pathways, warranting further investigation into the specific mechanisms and functional consequences of these protein associations.

Biological Activity

The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.

Species

Human

Source

HEK293

Tag

C-mFc

Accession

O14669 (E29-S109)

Gene ID

5639  [NCBI]

Molecular Construction
N-term
PRRG2 (E29-S109)
Accession # O14669
mFc
C-term
Synonyms
Transmembrane gamma-carboxyglutamic acid protein 2; Proline-rich Gla protein 2; PRGP2; TMG2
AA Sequence

EVFLGPPEAQSFLSSHTRIPRANHWDLELLTPGNLERECLEERCSWEEAREYFEDNTLTERFWESYIYNGKGGRGRVDVAS

Molecular Weight

Approximately 37 kDa.

Purity
  • Greater than 90% as determined by reducing SDS-PAGE.
Appearance

Lyophilized powder

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Storage & Stability

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping

Room temperature in continental US; may vary elsewhere.

Documentation

PRRG2 Protein, Human (HEK293, Fc) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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PRRG2 Protein, Human (HEK293, Fc)
Cat. No.:
HY-P77157
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