2. Metabolic Enzyme/Protease Vitamin D Related/Nuclear Receptor
  3. RAR/RXR
  4. Retinoic acid

Retinoic acid  (Synonyms: Vitamin A acid; all-trans-Retinoic acid; ATRA)

Cat. No.: HY-14649G
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Retinoic acid (Vitamin A acid) (GMP) is Retinoic acid (HY-14649) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Retinoic acid is an agonist of RAR nuclear receptors.

For research use only. We do not sell to patients.

Retinoic acid Chemical Structure

Retinoic acid Chemical Structure

CAS No. : 302-79-4

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10 mg USD 1200 In-stock
50 mg USD 3580 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Retinoic acid:

Retinoic acid Related Antibodies

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Description

Retinoic acid (Vitamin A acid) (GMP) is Retinoic acid (HY-14649) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Retinoic acid is an agonist of RAR nuclear receptors[1][2][3][4][5][6].

In Vitro

Retinoic acid (GMP) time- and dose- dependently induces differentiation of EC cells and ES cells into specific cell types[1].
Retinoic acid (GMP) induces partial differentiation of F9 embryonal carcinoma cells into endoderm cells[2].
Retinoic acid (GMP) (100 nM; 2-8 d) promotes photoreceptor differentiation in early postnatal retinal cultures[3].
Retinoic acid (GMP) (0.1 μM; 10-12 d) induces human SH-SY5Y neuroblastoma cells differentiation with long cell processes[4].
Retinoic acid (GMP) (0-10 μM; 48 h) dose-dependently induces morphologic differentiation of LA-N-1 human neuroblastoma cells[5].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Retinoic acid Related Antibodies
In Vivo

Retinoic acid (GMP) (0.3 μM; embryos are immersed in tank water containing retinoic acid) accelerates of rod differentiation is observed following 24 and 48 hours of application in zebrafish[6].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
Molecular Weight

300.44

Formula

C20H28O2
CAS No.
Appearance

Solid

Color

Light brown to yellow

SMILES

CC1(C)C(/C=C/C(C)=C/C=C/C(C)=C/C(O)=O)=C(C)CCC1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (166.42 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.3285 mL 16.6423 mL 33.2845 mL
5 mM 0.6657 mL 3.3285 mL 6.6569 mL
View the Complete Stock Solution Preparation Table

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C1

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Volume (start)

V1

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Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.3285 mL 16.6423 mL 33.2845 mL 83.2113 mL
5 mM 0.6657 mL 3.3285 mL 6.6569 mL 16.6423 mL
10 mM 0.3328 mL 1.6642 mL 3.3285 mL 8.3211 mL
15 mM 0.2219 mL 1.1095 mL 2.2190 mL 5.5474 mL
20 mM 0.1664 mL 0.8321 mL 1.6642 mL 4.1606 mL
25 mM 0.1331 mL 0.6657 mL 1.3314 mL 3.3285 mL
30 mM 0.1109 mL 0.5547 mL 1.1095 mL 2.7737 mL
40 mM 0.0832 mL 0.4161 mL 0.8321 mL 2.0803 mL
50 mM 0.0666 mL 0.3328 mL 0.6657 mL 1.6642 mL
60 mM 0.0555 mL 0.2774 mL 0.5547 mL 1.3869 mL
80 mM 0.0416 mL 0.2080 mL 0.4161 mL 1.0401 mL
100 mM 0.0333 mL 0.1664 mL 0.3328 mL 0.8321 mL
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Retinoic acid Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Retinoic acid (GMP)302-79-4Vitamin A acid (GMP) all-trans-Retinoic acid (GMP) ATRA (GMP)RAR/RXRRetinoic acid receptorsRetinoid X receptorsGMPdifferentiationECESF9 embryonal carcinoma cellSH-SY5Y neuroblastomaneuroblastomaInhibitorinhibitorinhibit

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