1. GPCR/G Protein
  2. Leukotriene Receptor
  3. Ritolukast

Ritolukast (Wy-48252) is an orally active aerosol leukotriene (LTD4/E4) receptor antagonist. Ritolukast can be used to inhibit the bronchoconstriction caused by aerosol LTD4 in guinea pigs, with an ID50 of 0.5mg/kg.

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Ritolukast Chemical Structure

Ritolukast Chemical Structure

CAS No. : 111974-60-8

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Description

Ritolukast (Wy-48252) is an orally active aerosol leukotriene (LTD4/E4) receptor antagonist. Ritolukast can be used to inhibit the bronchoconstriction caused by aerosol LTD4 in guinea pigs, with an ID50 of 0.5mg/kg[1].

Molecular Weight

382.36

Formula

C17H13F3N2O3S

CAS No.
SMILES

O=S(NC1=CC(OCC2=NC3=C(C=C2)C=CC=C3)=CC=C1)(C(F)(F)F)=O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Ritolukast Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Ritolukast
Cat. No.:
HY-156978
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