2. Protein Tyrosine Kinase/RTK
  3. ROS Kinase
  4. ROS kinases-IN-2

ROS kinases-IN-2 is a ROS kinase inhibitor with 21.53% inhibition at 10 μM.

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ROS kinases-IN-2 Chemical Structure

ROS kinases-IN-2 Chemical Structure

CAS No. : 687576-28-9

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1 mg USD 190 In-stock
5 mg USD 460 In-stock
10 mg USD 645 In-stock
25 mg USD 980 In-stock
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Based on 1 publication(s) in Google Scholar

ROS kinases-IN-2 Related Antibodies

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Description

ROS kinases-IN-2 is a ROS kinase inhibitor with 21.53% inhibition at 10 μM[1].

IC50 & Target

ROS[1]
Molecular Weight

437.53

Formula

C22H19N3O3S2
CAS No.
Appearance

Solid

Color

Yellow to brown

SMILES

O=C(C1=C2C=CC=CC2=NC(C3=CC=CS3)=C1)NCCC4=CC=C(S(=O)(N)=O)C=C4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (285.69 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2856 mL 11.4278 mL 22.8556 mL
5 mM 0.4571 mL 2.2856 mL 4.5711 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.2856 mL 11.4278 mL 22.8556 mL 57.1389 mL
5 mM 0.4571 mL 2.2856 mL 4.5711 mL 11.4278 mL
10 mM 0.2286 mL 1.1428 mL 2.2856 mL 5.7139 mL
15 mM 0.1524 mL 0.7619 mL 1.5237 mL 3.8093 mL
20 mM 0.1143 mL 0.5714 mL 1.1428 mL 2.8569 mL
25 mM 0.0914 mL 0.4571 mL 0.9142 mL 2.2856 mL
30 mM 0.0762 mL 0.3809 mL 0.7619 mL 1.9046 mL
40 mM 0.0571 mL 0.2857 mL 0.5714 mL 1.4285 mL
50 mM 0.0457 mL 0.2286 mL 0.4571 mL 1.1428 mL
60 mM 0.0381 mL 0.1905 mL 0.3809 mL 0.9523 mL
80 mM 0.0286 mL 0.1428 mL 0.2857 mL 0.7142 mL
100 mM 0.0229 mL 0.1143 mL 0.2286 mL 0.5714 mL
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ROS kinases-IN-2 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ROS kinases-IN-2687576-28-9ROS KinaseInhibitorinhibitorinhibit

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