2. Protein Tyrosine Kinase/RTK
  3. ROS Kinase
  4. ROS1-IN-1

ROS1-IN-1 (Compound 31) is a potent and selective ROS1 kinase inhibitor with an IC50 of 0.097 μM.

For research use only. We do not sell to patients.

ROS1-IN-1 Chemical Structure

ROS1-IN-1 Chemical Structure

CAS No. : 2883232-34-4

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ROS1-IN-1 Related Antibodies

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Description

ROS1-IN-1 (Compound 31) is a potent and selective ROS1 kinase inhibitor with an IC50 of 0.097 μM[1].

IC50 & Target

IC50: 0.097 μM (ROS1)[1]
In Vitro

ROS1-IN-1 (Compound 31) (1 μM) does not inhibit any other kinase at >50%, making it a truly selective starting point for optimization against ROS1[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

ROS1-IN-1 Related Antibodies
Molecular Weight

370.86

Formula

C17H15ClN6S
CAS No.
SMILES

CC1=NC(N(CC2=CC=C(C(Cl)=C2)C#N)C)=NC(NC3=NC=CS3)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Cell Assay

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
References
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ROS1-IN-1 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ROS1-IN-12883232-34-4ROS Kinasenon-small cell lung cancerROS1Inhibitorinhibitorinhibit

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HY-150974
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