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  3. Amino Acid Derivatives
  4. (S)-2-[(tert-Butoxycarbonyl)amino]-3-iodopropionic acid methyl ester

(S)-2-[(tert-Butoxycarbonyl)amino]-3-iodopropionic acid methyl ester  (Synonyms: Methyl (2S)-2-(tert-butoxycarbonylamino)-3-iodopropanoate; Methyl (S)-2-[(tert-butoxycarbonyl)amino]-3-iodopropanoate)

Cat. No.: HY-Z0424 Purity: 99.42%
SDS COA Handling Instructions

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(S)-2-[(tert-Butoxycarbonyl)amino]-3-iodopropionic acid methyl ester is an alanine derivative.

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(S)-2-[(tert-Butoxycarbonyl)amino]-3-iodopropionic acid methyl ester Chemical Structure

(S)-2-[(tert-Butoxycarbonyl)amino]-3-iodopropionic acid methyl ester Chemical Structure

CAS No. : 170848-34-7

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Based on 1 publication(s) in Google Scholar

(S)-2-[(tert-Butoxycarbonyl)amino]-3-iodopropionic acid methyl ester Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

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Description

(S)-2-[(tert-Butoxycarbonyl)amino]-3-iodopropionic acid methyl ester is an alanine derivative[1].

In Vitro

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

(S)-2-[(tert-Butoxycarbonyl)amino]-3-iodopropionic acid methyl ester Related Antibodies
Molecular Weight

329.13

Formula

C9H16INO4
CAS No.
Appearance

Solid

Color

White to light yellow

Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (303.83 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0383 mL 15.1916 mL 30.3831 mL
5 mM 0.6077 mL 3.0383 mL 6.0766 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% Saline

    Solubility: ≥ 2.5 mg/mL (7.60 mM); Clear solution

    This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).

    Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.

    Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
  • Protocol 2

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in Saline)

    Solubility: ≥ 2.5 mg/mL (7.60 mM); Clear solution

    This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).

    Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.

    Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
%
DMSO +
% 
+
%
Tween-80 +
%
Saline
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Calculation results:
Working solution concentration: mg/mL
Method for preparing stock solution: mg drug dissolved in μL  DMSO (Stock solution concentration: mg/mL).

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).
Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.
 If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation

Purity: 99.42%

SDS (394 KB)

COA (246 KB) RP-HPLC (384 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.0383 mL 15.1916 mL 30.3831 mL 75.9578 mL
5 mM 0.6077 mL 3.0383 mL 6.0766 mL 15.1916 mL
10 mM 0.3038 mL 1.5192 mL 3.0383 mL 7.5958 mL
15 mM 0.2026 mL 1.0128 mL 2.0255 mL 5.0639 mL
20 mM 0.1519 mL 0.7596 mL 1.5192 mL 3.7979 mL
25 mM 0.1215 mL 0.6077 mL 1.2153 mL 3.0383 mL
30 mM 0.1013 mL 0.5064 mL 1.0128 mL 2.5319 mL
40 mM 0.0760 mL 0.3798 mL 0.7596 mL 1.8989 mL
50 mM 0.0608 mL 0.3038 mL 0.6077 mL 1.5192 mL
60 mM 0.0506 mL 0.2532 mL 0.5064 mL 1.2660 mL
80 mM 0.0380 mL 0.1899 mL 0.3798 mL 0.9495 mL
100 mM 0.0304 mL 0.1519 mL 0.3038 mL 0.7596 mL
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(S)-2-[(tert-Butoxycarbonyl)amino]-3-iodopropionic acid methyl ester Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(S)-2-[(tert-Butoxycarbonyl)amino]-3-iodopropionic acid methyl ester170848-34-7Methyl (2S)-2-(tert-butoxycarbonylamino)-3-iodopropanoate Methyl (S)-2-[(tert-butoxycarbonyl)amino]-3-iodopropanoateAmino Acid DerivativesInhibitorinhibitorinhibit

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