2. Autophagy Metabolic Enzyme/Protease Immunology/Inflammation Apoptosis Others
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  4. Salicylic acid-13C6

Salicylic acid-13C6  (Synonyms: 2-Hydroxybenzoic acid-13C6)

Cat. No.: HY-B0167S1 Purity: ≥97.0%
COA Handling Instructions

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Salicylic acid-13C6 is the 13C-labeled Salicylic acid (HY-B0167). Salicylic acid is a precursor to and a metabolite of Aspirin (HY-14654), can inhibit cyclo-oxygenase-2 (COX-2) activity[1][2].

For research use only. We do not sell to patients.

Salicylic acid-<sup>13</sup>C<sub>6</sub> Chemical Structure

Salicylic acid-13C6 Chemical Structure

CAS No. : 1189678-81-6

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5 mg USD 2080 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Salicylic acid-13C6:

Salicylic acid-13C6 Related Antibodies

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COX COX-1 COX-2 COX-3

  • Biological Activity

  • Purity & Documentation

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Description

Salicylic acid-13C6 is the 13C-labeled Salicylic acid (HY-B0167). Salicylic acid is a precursor to and a metabolite of Aspirin (HY-14654), can inhibit cyclo-oxygenase-2 (COX-2) activity[1][2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Salicylic acid-13C6 Related Antibodies
Molecular Weight

144.08

Formula

C13C6H6O3
CAS No.
Unlabeled CAS

69-72-7
Appearance

Solid

Color

Off-white to light yellow

SMILES

OC([13C]1=[13C]([13CH]=[13CH][13CH]=[13CH]1)O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 50 mg/mL (347.03 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : 1 mg/mL (6.94 mM; Need ultrasonic)

H2O : 1 mg/mL (6.94 mM; Need ultrasonic)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.9406 mL 34.7029 mL 69.4059 mL
5 mM 1.3881 mL 6.9406 mL 13.8812 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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g

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥97.0%

COA (250 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / H2O / DMSO 1 mM 6.9406 mL 34.7029 mL 69.4059 mL 173.5147 mL
5 mM 1.3881 mL 6.9406 mL 13.8812 mL 34.7029 mL
DMSO 10 mM 0.6941 mL 3.4703 mL 6.9406 mL 17.3515 mL
15 mM 0.4627 mL 2.3135 mL 4.6271 mL 11.5676 mL
20 mM 0.3470 mL 1.7351 mL 3.4703 mL 8.6757 mL
25 mM 0.2776 mL 1.3881 mL 2.7762 mL 6.9406 mL
30 mM 0.2314 mL 1.1568 mL 2.3135 mL 5.7838 mL
40 mM 0.1735 mL 0.8676 mL 1.7351 mL 4.3379 mL
50 mM 0.1388 mL 0.6941 mL 1.3881 mL 3.4703 mL
60 mM 0.1157 mL 0.5784 mL 1.1568 mL 2.8919 mL
80 mM 0.0868 mL 0.4338 mL 0.8676 mL 2.1689 mL
100 mM 0.0694 mL 0.3470 mL 0.6941 mL 1.7351 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Salicylic acid-13C6 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Salicylic acid-13C61189678-81-62-Hydroxybenzoic acid-13C6AutophagyMitophagyEndogenous MetaboliteApoptosisIsotope-Labeled CompoundsCOXMitochondrial AutophagyCyclooxygenaseSalicylic acidAsprincyclo-oxygenase-2COX-2Inhibitorinhibitorinhibit

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