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SARM1-IN-2 is a SARM1 inhibitor extracted from patent WO2019236890A1 example 82. SARM1-IN-2 can be used for the research of axonal degeneration.

For research use only. We do not sell to patients.

SARM1-IN-2 Chemical Structure

SARM1-IN-2 Chemical Structure

CAS No. : 2396592-52-0

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5 mg USD 350 In-stock
10 mg USD 600 In-stock
25 mg USD 1200 In-stock
50 mg USD 1900 In-stock
100 mg USD 3000 In-stock
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Description

SARM1-IN-2 is a SARM1 inhibitor extracted from patent WO2019236890A1 example 82. SARM1-IN-2 can be used for the research of axonal degeneration[1].

Molecular Weight

326.37

Formula

C16H14N4O2S
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

N#CC1=C(NC2=C3C=CC(C)=NC3=CC=C2OC)SN(C)C1=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 10 mg/mL (30.64 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0640 mL 15.3200 mL 30.6401 mL
5 mM 0.6128 mL 3.0640 mL 6.1280 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.0640 mL 15.3200 mL 30.6401 mL 76.6002 mL
5 mM 0.6128 mL 3.0640 mL 6.1280 mL 15.3200 mL
10 mM 0.3064 mL 1.5320 mL 3.0640 mL 7.6600 mL
15 mM 0.2043 mL 1.0213 mL 2.0427 mL 5.1067 mL
20 mM 0.1532 mL 0.7660 mL 1.5320 mL 3.8300 mL
25 mM 0.1226 mL 0.6128 mL 1.2256 mL 3.0640 mL
30 mM 0.1021 mL 0.5107 mL 1.0213 mL 2.5533 mL
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SARM1-IN-2 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SARM1-IN-22396592-52-0OthersSARM1axonal degenerationInhibitorinhibitorinhibit

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