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SKI

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  • HY-P74491
    TRIB3 Protein, Human (sf9, GST)

    Tribbles homolog 3; TRB-3; SINK; C20orf97; NIPK; SKIP3

    		 Human Sf9 insect cells
    TRIB3 protein is an inactive kinase that centrally regulates the integrated stress response (ISR) and inhibits DDIT3/CHOP transcriptional activity. It causes DDIT3/CHOP-dependent cell death during endoplasmic reticulum (ER) stress, particularly in programmed neuronal cell death. TRIB3 Protein, Human (sf9, GST) is the recombinant human-derived TRIB3 protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of TRIB3 Protein, Human (sf9, GST) is 358 a.a., with molecular weight of ~65.8 kDa.
  • HY-P70316
    Elafin/Trappin-2 Protein, Human (HEK293, His)

    rHuElafin, His; Elafin; Elastase-Specific Inhibitor; ESI; Peptidase Inhibitor 3; PI-3; Protease inhibitor WAP3; SKIn-Derived Antileukoproteinase; SKALP; WAP Four-Disulfide Core Domain Protein 14; PI3; WAP3; WFDC14

    		 Human HEK293
    Elafin/Trappin-2, a skin-specific inhibitor of neutrophil and pancreatic elastase, safeguards tissues against elastase-mediated proteolysis. Its inhibitory range extends to the alpha-4-beta-2/CHRNA2-CHRNB2 nicotinic acetylcholine receptor. Elafin/Trappin-2 also weakly inhibits Kv11.1/KCNH2/ERG1 and transient receptor potential cation channel subfamily V member 1 (TRPV1), as reported in studies. Elafin/Trappin-2 Protein, Human (HEK293, His) is the recombinant human-derived Elafin/Trappin-2 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Elafin/Trappin-2 Protein, Human (HEK293, His) is 95 a.a., with molecular weight of 13-15 kDa.
  • HY-P76760
    CALML5 Protein, Human (His)

    Calmodulin-like protein 5; Calmodulin-like SKIn protein; CLSP

    		 Human E. coli
    The CALML5 protein is known for its calcium-binding ability and may be involved in terminal differentiation of keratinocytes, suggesting a role in skin cell maturation. Its association with transglutaminase 3 suggests cooperation in skin development function. CALML5 Protein, Human (His-GST) is the recombinant human-derived CALML5 protein, expressed by E. coli , with N-His, N-GST labeled tag. The total length of CALML5 Protein, Human (His-GST) is 146 a.a., with molecular weight of ~43 kDa.
  • HY-P70757G
    GMP SCF Protein, Human (HEK293, His)
    1 Publications Verification

    Kit Ligand; MGF; SCF; c-Kit ligand; KITLG; SKITLG

    		 Human HEK293
    SCF proteins are ligands for the KIT receptor-type protein tyrosine kinase and regulate a variety of cellular processes, including survival, proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration, and melanogenesis. Binding to KIT activates signaling pathways involving PIK3R1, AKT1, GRB2, RAS, RAF1, MAP kinase, STAT family members, and PLCG1, producing diacylglycerol and inositol 1,4,5-trisphosphate. GMP SCF Protein, Human (HEK293, His) is the recombinant human-derived SCF protein, expressed by HEK293 , with C-6*His labeled tag.
  • HY-P7767
    CTACK/CCL27 Protein, Human
    1 Publications Verification

    rHuCCL27; C-C Motif Chemokine 27; CC Chemokine ILC; Cutaneous T-Cell-Attracting Chemokine; CTACK; ESKIne; IL-11 R-Alpha-Locus Chemokine; SKInkine; Small-Inducible Cytokine A27; CCL27; ILC; SCYA27

    		 Human E. coli
    CTACK/CCL27 Protein, Human is a CC chemokine that binds to the chemokine receptor CCR10, attracts skin-associated memory T lymphocytes, mediates lymphocyte homing to skin sites, and plays a key role in skin inflammation. CTACK/CCL27 Protein, Human a recombinant human CTACK/CCL27 (F25-G112) protein expressed by E. coli.
  • HY-P7767A
    CTACK/CCL27 Protein, Human (His)

    rHuCCL27; C-C Motif Chemokine 27; CC Chemokine ILC; Cutaneous T-Cell-Attracting Chemokine; CTACK; ESKIne; IL-11 R-Alpha-Locus Chemokine; SKInkine; Small-Inducible Cytokine A27; CCL27; ILC; SCYA27

    		 Human E. coli
    CTACK/CCL27 protein selectively attracts skin-associated memory T-lymphocytes, mediating their homing to cutaneous sites through CCR10 binding. Crucial for skin immunity regulation, CCL27 exists as a monomer, dimer, and tetramer, with heparin promoting its oligomerization. Interaction with TNFAIP6, particularly through its Link domain, implies regulatory roles in skin immune responses and inflammation within the skin microenvironment. CTACK/CCL27 Protein, Human (His) is the recombinant human-derived CTACK/CCL27 protein, expressed by E. coli , with N-His labeled tag.

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