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Results for "

<i>Escherichia coli</i> (<i>E. coli</i>)、<i>Klebsiella pneumoniae</i>

" in MedChemExpress (MCE) Product Catalog:

13

Inhibitors & Agonists

1

Peptides

2

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-124679
    DS86760016

    		Bacterial Infection
    DS86760016 is a potent leucyl-tRNA synthetase (LeuRS) inhibitor with activity against multidrug-resistant (MDR) Gram-negative bacteria, such as Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa. DS86760016 inhibits LeuRS enzymes from Escherichia coli, Pseudomonas aeruginosa, and Acinetobacter baumannii, with IC50s of 0.38, 0.62, and 0.16 μM, respectively .
    DS86760016
  • HY-W012444
    Glyceryl 1-monooctanoate

    		Antibiotic Fungal Infection
    Glyceryl 1-monooctanoate is a glycerol monolaurate derivative. Glyceryl 1-monooctanoate is a broad-spectrum antimicrobial, suppresses the growth of pathogenic yeast (Candida albicans and Candida parapsilosis), as well as Gram-positive (Staphylococcus aureus) and Gram-negative (Escherichia coli, Klebsiella pneumoniae) bacteria .
    Glyceryl 1-monooctanoate
  • HY-129331
    Neothramycin A

    		Antibiotic Bacterial Fungal Infection Cancer
    Neothramycin A is an antibiotic, which can be isolated from Streptomyces. Neothramycin A exhibits board spectrum antimicrobial activity, inhibits Staphylococcus aureus, Klebsiella pneumoniae, Escherichia coli W677, and Saccharomyces cerevisia with MIC of 25-50 μg/mL. Neothramycin A exhibits antitumor efficacy against leukemia in mouse models .
    Neothramycin A
  • HY-130066
    Fortimicin C

    		Antibiotic Bacterial Infection
    Fortimicin C is an antibiotic, which can be isolated from Micromonospora olivoasterospora. Fortimicin C exhibits broad-spectrum antibacterial activity, inhibits Escherichia coli, Staphylococcus aureus, Bacillus subtilis, Klebsiella pneumoniae, Salmonella typhosa and Serratia marcescens, with MICs of 0.16-0.64 μg/mL. Fortimicin C is resistant against aminoglycoside inactivating enzymes .
    Fortimicin C
  • HY-P5734
    Bactenecin 5

    		Bacterial Infection
    Bactenecin 5 is a bovine antibacterial peptide. Bactenecin 5 is active against Escherichia coli, Salmonella typhimurium, and Klebsiella pneumoniae. T, with MIC values of 12-25 μg/mL .
    Bactenecin 5
  • HY-114860
    LY 215891

    		Bacterial Inflammation/Immunology
    LY 215891 (compound 6a) exhibits potent Gram-positive and Gram-negative antibacterial activity with MICs of 0.015 μg/mL and 0.06 μg/mL for Klebsiella pneumoniae X26 and Escherichia coli EC14, respectively .
    LY 215891
  • HY-107064
    Cefroxadine

    CGP 9000; Oraspor

    		 Bacterial Antibiotic Infection
    Cefroxadine (CGP 9000) is an orally active cephalosporin antibiotic. Cefroxadine is more effective than cephalexin against Escherichia coli and Klebsiella pneumoniae with MIC values of 3.13 and 1.56 μg/mL respectively with a concentration of 10 6 μg/mL. Cefroxadine can be used for the research of infection .
    Cefroxadine
  • HY-170308
    IspE kinase-IN-1

    		Bacterial Infection
    IspE kinase-IN-1 (compound 4) is a potent IspE kinase inhibitor with IC50 values of 6.2, 5.2 µM for EclspE, KplspE, respectively .
    IspE kinase-IN-1
  • HY-150767
    KPC-2-IN-2

    		Bacterial Infection
    KPC-2-IN-2 (Compound 6c) is a potent Klebsiella pneumoniae carbapenemase (KPC-2) inhibitor (Ki=0.038 μM). KPC-2-IN-2 can enhance the activity of cefotaxime in KPC-2 expressing Escherichia coli .
    KPC-2-IN-2
  • HY-144284
    MsbA-IN-5

    		Bacterial Infection
    MsbA-IN-5 (compound 40) is a potent and highly selective MsbA inhibitor with an IC50 value of 2 nM. MsbA-IN-5 has inhibitory activity against Escherichia coli, Klebsiella pneumoniae, and Enterobacter cloacae with MICs of 12 μM, 12 μM and 25 μM, respectively. MsbA-IN-5 can be used for researching anti-Gram-negative bacteria .
    MsbA-IN-5
  • HY-159969
    MLEB-22043

    		Bacterial Antibiotic Infection
    MLEB-22043 is a synthetic siderophore-monobactam conjugate that is taken up into bacteria via its synthetic siderophore component by TonB-dependent transporters. Once inside the bacteria, it exerts antibacterial activity through its β-lactam component. MLEB-22043 is a broad-spectrum antibiotic with significant inhibitory activity against Klebsiella pneumoniae, Escherichia coli, Acinetobacter baumannii, and Pseudomonas aeruginosa .
    MLEB-22043
  • HY-168674
    Antibacterial agent 255

    		Bacterial Infection
    Antibacterial agent 255 (compound (±)-1) is a potent antibacterial agent. Antibacterial agent 255 is a potent and selective 4-diphosphocytidyl-2-C-methyl-D-erythritol (IspE) inhibitor with IC50 values of 13.0, 8.0, 20 µM for EclspE, KplspE, AblspE, respectively .
    Antibacterial agent 255
  • HY-161404
    Antibacterial agent 202

    		Bacterial Infection
    Antibacterial agent 202 (compound 45c) is a low cytotoxicity bacterial inhibitor with good activity against Gram-negative bacteria, including Escherichia coli, Klebsiella pneumonia, especially Pseudomonas aeruginosa, (MIC (minimum inhibitory concentration)=7.8-31.25 μM). Antibacterial agent 202 can exert antibacterial activity by destroying the integrity of cell membranes and can be used in the research of bacterial infections .
    Antibacterial agent 202

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