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α-chymotrypsin

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Biochemical Assay Reagents (1) Elastase (2) PSMA (1)
By Research Areas:	Infection (2) Inflammation/Immunology (1)

4

Inhibitors & Agonists

1

Biochemical Assay Reagents

4

Peptides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

FK706	Elastase	Inflammation/Immunology
FK706 is a potent, slow-binding and competitive inhibitor of human neutrophil elastase with an IC₅₀ of 83 nM and a K_i of 4.2 nM. FK706 also inhibits mouse neutrophil elastase and porcine pancreatic elastase with IC₅₀s of 22 nM and 100 nM, respectively, and has no inhibitory activity against other serine proteinases such as human pancreatic trypsin, human pancreatic α-chymotrypsin and human leukocyte cathepsin G. FK706 has anti-inflammatory effect .

CDD-3290	PSMA Elastase	Others
CDD-3290 (Compound 20) is a prostate-specific antigen (PSA) inhibitor with a K_i value of 216 nM. CDD-3290 also inhibits α-chymotrypsin and elastase .

H-Gly-Oet	Others	Others
H-Gly-Oet can be coupled with Z-Pro-Leu-OEt for the synthesis of tripeptide Z-Pro-Leu-Gly-OEt by thermolysin and α-chymotrypsin catalysis .

5-Bromo-4-chloro-1H-indol-3-yl nonanoate	Biochemical Assay Reagents	Others
5-Bromo-4-chloro-1H-indol-3-yl nonanoate is a fluorescent substrate used to detect enzymes. The substrate reacts with various enzymes to produce a fluorescent product, which has been shown to be active against β-galactosidase, α-chymotrypsin, and β-glucuronidase.

Cat. No.	Product Name	Type

5-Bromo-4-chloro-1H-indol-3-yl nonanoate	Cell Assay Reagents
5-Bromo-4-chloro-1H-indol-3-yl nonanoate is a fluorescent substrate used to detect enzymes. The substrate reacts with various enzymes to produce a fluorescent product, which has been shown to be active against β-galactosidase, α-chymotrypsin, and β-glucuronidase.

Cat. No.	Product Name	Target	Research Area

Suc-AAPF-AMC 1 Publications Verification Suc-Ala-Ala-Pro-Phe-AMC	Peptides	Others
Suc-AAPF-AMC is an α-chymotrypsin fluorogenic substrate for the quantitative determination of chymotrypsin activity .

Eglin c (41-49)	Peptides	Others
Eglin c (41-49) is a peptide fragment related to eglin c. Eglin c (41-49) shows inhibitory effects to cathepsin G and α-chymotrypsin with K_i values of 42 and 20 μM, respectively .

SPSB2-iNOS inhibitory cyclic peptide-1	Peptides	Infection
SPSB2-iNOS inhibitory cyclic peptide-1 is an inhibitor for the interaction of SPRY domain and SOCS-box protein 2 (SPSB2) and iNOS, through binding SPSB2 on iNOS site with K_D of 4.4 nM. SPSB2-iNOS inhibitory cyclic peptide-1 is resistant to the proteases pepsin, trypsin and α-chymotrypsin. SPSB2-iNOS inhibitory cyclic peptide-1 is stable in human plasma and in oxidative environment .

SPSB2-iNOS inhibitory cyclic peptide-1 TFA	Peptides	Infection
SPSB2-iNOS inhibitory cyclic peptide-1 TFA is the TFA salt form of SPSB2-iNOS inhibitory cyclic peptide-1(HY-P10383). SPSB2-iNOS inhibitory cyclic peptide-1 is an inhibitor for the interaction of SPRY domain and SOCS-box protein 2 (SPSB2) and iNOS, through binding SPSB2 on iNOS site with K_D of 4.4 nM. SPSB2-iNOS inhibitory cyclic peptide-1 is resistant to the proteases pepsin, trypsin and α-chymotrypsin. SPSB2-iNOS inhibitory cyclic peptide-1 is stable in human plasma and in oxidative environment .

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