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15-lipoxygenase

" in MedChemExpress (MCE) Product Catalog:

25

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2

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  • HY-P74437
    15 Lipoxygenase 2 Protein, Human (sf9)

    Polyunsaturated fatty acid lipoxygenase ALOX15B; 15-LOX-2; ALOX15B

    		 Human Sf9 insect cells
    15-Lipoxygenase 2 (15-LOX2) is a non-heme iron-containing dioxygenase crucial for peroxidation of polyunsaturated fatty acids (PUFAs). It exhibits peroxidase activity on arachidonate and linoleate, producing bioactive lipid mediators. Oxygenating arachidonyl derivatives, it generates 15-HETE-G, a peroxisome proliferator-activated receptor alpha agonist. 15-LOX2 class-switches pro-inflammatory mediators, participates in DHA oxidations to produce specialized pro-resolving mediators, and may influence cell cycle progression, proliferation, cytokine secretion, and macrophage differentiation. Importantly, it shows substrate specificity by not converting arachidonic acid to (15S)-HPETE. 15 Lipoxygenase 2 Protein, Human (sf9) is the recombinant human-derived 15 Lipoxygenase 2 protein, expressed by Sf9 insect cells , with tag free. and with residual Gly-Pro in N-terminal (not related to functional changes) mutation. The total length of 15 Lipoxygenase 2 Protein, Human (sf9) is 676 a.a., with molecular weight of 62-66 kDa.
  • HY-P74436
    15 Lipoxygenase 2 Protein, Human (sf9, His-GST)

    Polyunsaturated fatty acid lipoxygenase ALOX15B; 15-LOX-2; ALOX15B

    		 Human Sf9 insect cells
    15-lipoxygenase 2 (15-LOX2) is a nonheme iron-containing dioxygenase essential for the peroxidation of polyunsaturated fatty acids (PUFA). It exhibits peroxidase activity towards arachidonic acid and linoleic acid, producing bioactive lipid mediators. 15 Lipoxygenase 2 Protein, Human (sf9, His-GST) is the recombinant human-derived 15 Lipoxygenase 2 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of 15 Lipoxygenase 2 Protein, Human (sf9, His-GST) is 676 a.a., with molecular weight of ~93 kDa.