Search Result
Results for "
2'-Deoxyguanosine-d
" in MedChemExpress (MCE) Product Catalog:
7
Biochemical Assay Reagents
28
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-17563S2
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Deoxyguanosine-13C10; Guanine deoxyriboside-13C10
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Isotope-Labeled Compounds
Endogenous Metabolite
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Cancer
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2'-Deoxyguanosine- 13C10 (Deoxyguanosine- 13C10; Guanine deoxyriboside- 13C10) is 13C-labeled 2'-Deoxyguanosine (HY-17563). 2'-Deoxyguanosine (Deoxyguanosine) is deoxyguanosine.
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- HY-17563R
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Deoxyguanosine (Standard); Guanine deoxyriboside (Standard)
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Reference Standards
Endogenous Metabolite
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Cancer
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2'-Deoxyguanosine (Standard) is the analytical standard of 2'-Deoxyguanosine. This product is intended for research and analytical applications. 2’-Deoxyguanosine (Deoxyguanosine) is a purine nucleoside with a variety of biological activities. 2’-Deoxyguanosine can induce DNA division in mouse thymus cells. 2’-Deoxyguanosine is a potent cell division inhibitor in plant cells .
In Vitro: 2'-Deoxyguanosine inhibits the clonal growth of HL-60 and K562 leukemia cells with IC50 values of 50 and 80 μM, respectively .
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- HY-D0185S4
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Endogenous Metabolite
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Metabolic Disease
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2'-Deoxyguanosine- 13C10, 15N5 (monohydrate) is the 13C and 15N labeled 2'-Deoxyguanosine monohydrate . 2'-Deoxyguanosine monohydrate is an endogenous metabolite.
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- HY-17563S3
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Deoxyguanosine-d13; Guanine deoxyriboside-d13
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Isotope-Labeled Compounds
Endogenous Metabolite
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Cancer
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2'-Deoxyguanosine-d13 (Deoxyguanosine-d13; Guanine deoxyriboside-d13) is deuterium labeled 2'-Deoxyguanosine (HY-17563). 2'-Deoxyguanosine (Deoxyguanosine) is deoxyguanosine.
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-
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- HY-D0185S1
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- HY-D0185S
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- HY-W753153
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-
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- HY-W767614
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-
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- HY-W721188
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N2-Ethyl-2'-Deoxyguanosine-d6
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Isotope-Labeled Compounds
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Others
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2'-Deoxy-N-ethylguanosine-d6 (N2-Ethyl-2'-deoxyguanosine-d6) is the deuterium labeled 2-(Ethylamino)-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one (HY-W013267).
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- HY-17563S4
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Deoxyguanosine-15N5; Guanine deoxyriboside-15N5
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Isotope-Labeled Compounds
Endogenous Metabolite
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Cancer
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2'-Deoxyguanosine- 15N5 (Deoxyguanosine- 15N5; Guanine deoxyriboside- 15N5) is 15N labeled 2'-Deoxyguanosine (HY-17563). 2'-Deoxyguanosine (Deoxyguanosine) is deoxyguanosine.
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- HY-17563
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Deoxyguanosine; Guanine deoxyriboside
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Endogenous Metabolite
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Cancer
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2’-Deoxyguanosine (Deoxyguanosine) is a purine nucleoside with a variety of biological activities. 2’-Deoxyguanosine can induce DNA division in mouse thymus cells. 2’-Deoxyguanosine is a potent cell division inhibitor in plant cells .
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-
-
- HY-W338294S2
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-
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- HY-17563S
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Deoxyguanosine-13C,15N2; Guanine deoxyriboside-13C,15N2
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Isotope-Labeled Compounds
Endogenous Metabolite
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Cancer
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2'-Deoxyguanosine- 13C, 15N2 (Deoxyguanosine- 13C, 15N2; Guanine deoxyriboside- 13C, 15N2) is the 13C- and 15N-labeled labeled 2'-Deoxyguanosine (HY-17563). 2’-Deoxyguanosine (Deoxyguanosine) is a purine nucleoside with a variety of biological activities. 2’-Deoxyguanosine can induce DNA division in mouse thymus cells. 2’-Deoxyguanosine is a potent cell division inhibitor in plant cells .
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- HY-W011540S
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Endogenous Metabolite
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Cancer
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8-Hydroxy-2'-deoxyguanosine- 15N5 is the 15N labeled 8-Hydroxy-2'-deoxyguanosine . 8-Hydroxy-2'-deoxyguanosine is a critical biomarker of oxidative stress and carcinogenesis .
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- HY-W653916
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8-Oxo-2-Deoxyguanosine-13C,15N2
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Isotope-Labeled Compounds
Endogenous Metabolite
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Cancer
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8-Hydroxy-2'-deoxyguanosine- 13C, 15N2 is 13C and 15N labeled 8-Hydroxy-2'-deoxyguanosine. 8-Hydroxy-2'-deoxyguanosine is a critical biomarker of oxidative stress and carcinogenesis .
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- HY-W048492
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7-Deaza-7-Iodo-2'-Deoxyguanosine
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DNA/RNA Synthesis
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Others
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7-Iodo-7-deaza-2'-deoxyguanosine (7-Deaza-7-Iodo-2'-deoxyguanosine) is a deoxyguanosine derivative that can be used in DNA synthesis and sequencing reactions .
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-
-
- HY-W013159S
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dGMP-13C10,15N5
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Isotope-Labeled Compounds
Endogenous Metabolite
Nucleoside Antimetabolite/Analog
|
Metabolic Disease
|
2'-Deoxyguanosine 5'-monophosphate- 13C10, 15N5 (dGMP- 13C10, 15N5) disodium is the 13C and 15N labeled 2'-Deoxyguanosine 5'-monophosphate disodium (HY-W013159). 2'-Deoxyguanosine 5'-monophosphate (5′-dGMP) disodium is a mononucleotide having guanine as the nucleobase. 2'-Deoxyguanosine 5'-monophosphate disodium is a reactant involved in analysis of self-assembling in solution and nucleation/growth of G-qudruplexes, nucleophilic trapping and reductive alkylation. 2'-Deoxyguanosine 5'-monophosphate disodium can be used as an oxidizable target. 2'-Deoxyguanosine 5'-monophosphate disodium is a nucleic acid guanosine triphosphate (GTP) derivative and is a nucleotide precursor used in DNA synthesis .
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- HY-W013159
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5′-dGMP disodium
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Endogenous Metabolite
Nucleoside Antimetabolite/Analog
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Metabolic Disease
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2'-Deoxyguanosine 5'-monophosphate (5′-dGMP) disodium is a mononucleotide having guanine as the nucleobase. 2'-Deoxyguanosine 5'-monophosphate disodium is a reactant involved in analysis of self-assembling in solution and nucleation/growth of G-qudruplexes, nucleophilic trapping and reductive alkylation. 2'-Deoxyguanosine 5'-monophosphate disodium can be used as an oxidizable target. 2'-Deoxyguanosine 5'-monophosphate disodium is a nucleic acid guanosine triphosphate (GTP) derivative and is a nucleotide precursor used in DNA synthesis .
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- HY-W768213
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Isotope-Labeled Compounds
Endogenous Metabolite
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Metabolic Disease
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2'-Deoxyguanosine monohydrate- 13C5 is the 13C-labeled 2'-Deoxyguanosine monohydrate (HY-D0185). 2'-Deoxyguanosine monohydrate is a nucleoside composed of guanine and deoxyribose, and is one of the basic building blocks of DNA. In the oxidation reaction mediated by singlet oxygen 1O2, the guanine base of 2'-Deoxyguanosine is easily oxidized to generate two major products, 4,8-dihydro-4-hydroxy-8-oxodG and 7,8-dihydro-8-oxodG. The oxidation products of 2'-Deoxyguanosine monohydrate may participate in DNA damage, which may affect gene expression or induce cancer .
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- HY-17563S1
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Deoxyguanosine-13C10,15N5; Guanine deoxyriboside-13C10,15N5
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Isotope-Labeled Compounds
Endogenous Metabolite
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Cancer
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2'-Deoxyguanosine- 13C10, 15N5 (Deoxyguanosine- 13C10, 15N5; Guanine deoxyriboside- 13C10, 15N5) is a 13C- and 15N-labeled 2'-Deoxyguanosine (HY-17563).
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- HY-151688
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ADC Linker
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Others
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6-O-Propynyl-2'-deoxyguanosine is a click chemistry reagent containing an alkyne group. 6-O-Propynyl-2'-deoxyguanosine can be used for the research of various biochemical .
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- HY-W393970S4
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5'-Deoxyguanylic acid-15N5 dilithium
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Isotope-Labeled Compounds
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Others
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2′-Deoxyguanosine 5′-monophosphate- 15N5 (5'-Deoxyguanylic acid- 15N5) dilithium is 15N labeled 2′-Deoxyguanosine 5′-monophosphate (HY-W393970).
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- HY-W393970S1
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5'-Deoxyguanylic acid-d12 dilithium
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Isotope-Labeled Compounds
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Others
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2′-Deoxyguanosine 5′-monophosphate-d12 (5'-Deoxyguanylic acid-d12) dilithium is deuterium labeled 2′-Deoxyguanosine 5′-monophosphate (HY-W393970).
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- HY-W393970S2
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5'-Deoxyguanylic acid-13C10 dilithium
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Isotope-Labeled Compounds
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Others
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2′-Deoxyguanosine 5′-monophosphate- 13C10 (5'-Deoxyguanylic acid- 13C10) dilithium is 13C-labeled 2′-Deoxyguanosine 5′-monophosphate (HY-W393970).
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- HY-W767399
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Isotope-Labeled Compounds
Nucleoside Antimetabolite/Analog
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Cancer
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8-Bromo-2'-deoxyguanosine- 13C, 15N2 is the 13C- and 15N-labeled 8-Bromo-2'-deoxyguanosine (HY-W011168). 8-Bromo-2'-deoxyguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-W011540
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8-Oxo-2-Deoxyguanosine
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Endogenous Metabolite
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Cancer
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8-Hydroxy-2'-deoxyguanosine is a critical biomarker of oxidative stress and carcinogenesis.
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- HY-W393970S3
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5'-Deoxyguanylic acid-13C10,15N5 dilithium
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Isotope-Labeled Compounds
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Others
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2′-Deoxyguanosine 5′-monophosphate- 13C10, 15N5 (5'-Deoxyguanylic acid- 13C10, 15N5) dilithium is 13C and 15N-labeled 2′-Deoxyguanosine 5′-monophosphate (HY-W393970).
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- HY-D0185
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Endogenous Metabolite
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Metabolic Disease
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2'-Deoxyguanosine monohydrate is a nucleoside composed of guanine and deoxyribose, and is one of the basic building blocks of DNA. In the oxidation reaction mediated by singlet oxygen 1O2, the guanine base of 2'-Deoxyguanosine is easily oxidized to generate two major products, 4,8-dihydro-4-hydroxy-8-oxodG and 7,8-dihydro-8-oxodG. The oxidation products of 2'-Deoxyguanosine monohydrate may participate in DNA damage, which may affect gene expression or induce cancer .
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- HY-W393970S
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5'-Deoxyguanylic acid-15N5,d12 dilithium
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Isotope-Labeled Compounds
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Others
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2′-Deoxyguanosine 5′-monophosphate- 15N5,d12 (5'-Deoxyguanylic acid- 15N5,d12) dilithium is deuterium and 15N labeled 2′-Deoxyguanosine 5′-monophosphate (HY-W393970).
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- HY-18762
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6-thio-dG; β-TGdR
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DNA/RNA Synthesis
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Cancer
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6-Thio-2'-Deoxyguanosine is a nucleoside analogue that can be incorporated into de novo-synthesized telomeres by telomerase.
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- HY-W016011
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- HY-W008661
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dGTP (trisodium) solution (100mM); 2'-Deoxyguanosine-5'-triphosphate (trisodium) solution (100mM)
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DNA/RNA Synthesis
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Others
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Deoxyguanosine triphosphate (dGTP) trisodium solution (100mM) is a nucleotide precursor in cells for DNA synthesis. Deoxyguanosine triphosphate trisodium salt is used in reverse transcription-polymerase chain reaction (RT-PCR) for DNA amplification .
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- HY-W250161
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7-Deaza-2'-dGTP
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Telomerase
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Cancer
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7-Deaza-2′-deoxyguanosine 5′-triphosphate (7-Deaza-2'-dGTP), a nucleotide analogue, is a telomerase inhibitor (IC50: 11 μM) .
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- HY-138616S1
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2'-Deoxyguanosine-5'-triphosphate-d14 dilithium
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Isotope-Labeled Compounds
DNA/RNA Synthesis
Nucleoside Antimetabolite/Analog
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Infection
Cancer
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dGTP-d14 (2'-Deoxyguanosine-5'-triphosphate-d14) dilithium is deuterium labeled dGTP (HY-138616). dGTP (2'-Deoxyguanosine-5'-triphosphate), a guanosine nucleotide, can be used in deoxyribonucleic acid synthesis. Guanosine nucleotides (GDP, GTP, dGDP, and dGTP) are highly susceptible to oxidative damage to 8-oxo-GDP (8-O-GDP), 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.
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- HY-138616S3
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2'-Deoxyguanosine-5'-triphosphate-13C10 dilithium
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Isotope-Labeled Compounds
DNA/RNA Synthesis
Nucleoside Antimetabolite/Analog
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Infection
Cancer
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dGTP- 13C10 (2'-Deoxyguanosine-5'-triphosphate- 13C10) dilithium is 13C-labeled dGTP (HY-138616). dGTP (2'-Deoxyguanosine-5'-triphosphate), a guanosine nucleotide, can be used in deoxyribonucleic acid synthesis. Guanosine nucleotides (GDP, GTP, dGDP, and dGTP) are highly susceptible to oxidative damage to 8-oxo-GDP (8-O-GDP), 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.
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- HY-138616S
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2'-Deoxyguanosine-5'-triphosphate-155
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Isotope-Labeled Compounds
DNA/RNA Synthesis
Nucleoside Antimetabolite/Analog
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Infection
Cancer
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dGTP- 15N5 (2'-Deoxyguanosine-5'-triphosphate- 15N5) dilithium is 15N labeled dGTP (HY-138616). dGTP (2'-Deoxyguanosine-5'-triphosphate), a guanosine nucleotide, can be used in deoxyribonucleic acid synthesis. Guanosine nucleotides (GDP, GTP, dGDP, and dGTP) are highly susceptible to oxidative damage to 8-oxo-GDP (8-O-GDP), 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.
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- HY-148169
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- HY-138616S4
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2'-Deoxyguanosine-5'-triphosphate-13C10,15N5 dilithium
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Isotope-Labeled Compounds
DNA/RNA Synthesis
Nucleoside Antimetabolite/Analog
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Infection
Cancer
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dGTP- 13C10, 15N5 (2'-Deoxyguanosine-5'-triphosphate- 13C10, 15N5) dilithium is 13C and 15N-labeled dGTP (HY-138616). dGTP (2'-Deoxyguanosine-5'-triphosphate), a guanosine nucleotide, can be used in deoxyribonucleic acid synthesis. Guanosine nucleotides (GDP, GTP, dGDP, and dGTP) are highly susceptible to oxidative damage to 8-oxo-GDP (8-O-GDP), 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.
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- HY-138616S2
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2'-Deoxyguanosine-5'-triphosphate-15N5,d14 dilithium
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Isotope-Labeled Compounds
DNA/RNA Synthesis
Nucleoside Antimetabolite/Analog
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Infection
Cancer
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dGTP- 15N5,d14 (2'-Deoxyguanosine-5'-triphosphate- 15N5,d14) dilithium is deuterium and 15N labeled dGTP (HY-138616). dGTP (2'-Deoxyguanosine-5'-triphosphate), a guanosine nucleotide, can be used in deoxyribonucleic acid synthesis. Guanosine nucleotides (GDP, GTP, dGDP, and dGTP) are highly susceptible to oxidative damage to 8-oxo-GDP (8-O-GDP), 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.
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- HY-152351
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Nucleoside Antimetabolite/Analog
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Cancer
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8-Bromo-3’-deoxyguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-W011168
-
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Nucleoside Antimetabolite/Analog
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Cancer
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8-Bromo-2'-deoxyguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-W013330
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Guanosine, 3'-deoxy-
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Nucleoside Antimetabolite/Analog
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Cancer
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3′-Deoxyguanosine (Guanosine, 3'-deoxy-) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-152367
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Nucleoside Antimetabolite/Analog
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Cancer
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8-Hydroxy-3’-deoxyguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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-
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- HY-154243
-
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Nucleoside Antimetabolite/Analog
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Cancer
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8-Methyl-2’-deoxyguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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-
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- HY-152354
-
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Nucleoside Antimetabolite/Analog
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Cancer
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8-Benzyloxy-3’-deoxyguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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-
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- HY-154470
-
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Nucleoside Antimetabolite/Analog
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Cancer
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8-Aza-2’-deoxyguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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-
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- HY-134991
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-
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- HY-134991A
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-
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- HY-W010702
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N2-Isobutyryl-5′-O-(4,4′-dimethoxytrityl)-2′-Deoxyguanosine
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DNA/RNA Synthesis
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Others
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5'-O-DMT-N2-ibu-dG (N2-Isobutyryl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyguanosine) is a deoxynucleoside which can be used in the preparation of oligonucleotides .
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-
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- HY-138616
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2'-Deoxyguanosine-5'-triphosphate
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DNA/RNA Synthesis
Nucleoside Antimetabolite/Analog
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Infection
Cancer
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dGTP (2'-Deoxyguanosine-5'-triphosphate), a guanosine nucleotide, can be used in deoxyribonucleic acid synthesis. Guanosine nucleotides (GDP, GTP, dGDP, and dGTP) are highly susceptible to oxidative damage to 8-oxo-GDP (8-O-GDP), 8-O-dGTP, 8-O-GTP, and 8-O-dGTP .
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- HY-W425099
-
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DNA/RNA Synthesis
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Others
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2'-Deoxyguanosine-(N-iBu)-3'-methyl-phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
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- HY-132144
-
-
- HY-W008661A
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dGTP trisodium,100 mM Solution,PCR Grade; 2'-Deoxyguanosine-5'-triphosphate trisodium,100 mM Solution,PCR Grade
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Biochemical Assay Reagents
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Others
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Deoxyguanosine triphosphate trisodium,100 mM Solution,PCR Grade (dGTP trisodium,100 mM Solution,PCR Grade) is one of the raw materials used by DNA polymerase to synthesize long DNA chains during DNA replication. Deoxyguanosine triphosphate trisodium,100 mM Solution,PCR Grade (dGTP trisodium,100 mM Solution,PCR Grade) is used in reverse transcription polymerase chain reaction (RT-PCR) for DNA amplification. This product is provided in the form of aqueous solution .
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- HY-W098689
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2'-Deoxy-N2-dimethylaminomethylene-guanosine
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Nucleoside Antimetabolite/Analog
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Others
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Dmf-dg (2'-Deoxy-N2-dimethylaminomethylene-guanosine) is a deoxyguanosine (dG) nucleoside protected by the dimethylaminomethylamidine (DMF) base and can be used for oligonucleotide synthesis .
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- HY-132140
-
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Biochemical Assay Reagents
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Others
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7-Deaza-7-propargylamino-3'-azidomethyl-dGTP is an analog of deoxyguanosine triphosphate (dGTP) that widely used in the next generation sequencing (NGS) .
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- HY-131803
-
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Nucleoside Antimetabolite/Analog
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Inflammation/Immunology
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Urolignoside is an antioxidant with free radical scavenging activity. Urolignoside potently scavenges DPPH radical, and exhibits antioxidant to β-carotene-lineoleate model . 3'-Azido-3'-deoxyguanosine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-131605
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GCV-TP
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Endogenous Metabolite
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Infection
Cancer
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Ganciclovir triphosphate (GCV-TP) is a synthetic 2'-deoxyguanosine analog with activity in inhibiting human cytomegalovirus (CMV) replication. Ganciclovir triphosphate is effective against CMV infection by binding to viral DNA polymerase and interfering with viral DNA synthesis. Ganciclovir triphosphate has an IC50 of 0.01 μM and has good antiviral effects against CMV strains from humans, monkeys, mice, and guinea pigs. Ganciclovir triphosphate has also been used in gene-directed enzyme prodrug inhibition for cancer inhibition .
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- HY-132140A
-
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Biochemical Assay Reagents
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Others
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7-Deaza-7-propargylamino-3'-azidomethyl-dGTP triethylamine is an analog of deoxyguanosine triphosphate (dGTP) that widely used in the next generation sequencing (NGS) .
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- HY-13637S
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BW 759-d5; 2'-Nor-2'-Deoxyguanosine-d5
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Isotope-Labeled Compounds
CMV
HSV
Antibiotic
Nucleoside Antimetabolite/Analog
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Infection
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Ganciclovir-d5 is the deuterium labeled Ganciclovir. Ganciclovir (BW 759), a nucleoside analogue, is an orally active antiviral agent with activity against CMV. Ganciclovir also has activity in vitro against members of the herpes group and some other DNA viruses. Ganciclovir inhibits the in vitro replication of human herpes viruses (HSV 1 and 2, CMV) and adenovirus serotypes 1, 2, 4, 6, 8, 10, 19, 22 and 28. Ganciclovir has an IC50 of 5.2 μM for feline herpesvirus type-1 (FHV-1) .
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- HY-145538
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5'-Deoxyguanylic acid disodium hydrate
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DNA/RNA Synthesis
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Others
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2'-Deoxyguanosine 5'-monophosphate (5'-Deoxyguanylic acid; dGMP) disodium hydrate is an oxidizable target of the photosensitizer pterin (PT) and can be used to evaluate the photosensitizing properties of biopterins (such as Bip, Fop and Cap) . Pterin causes a photosensitive reaction of dGMP under UV-A radiation, causing damage to DNA molecules. There are two main mechanisms for the photosensitive oxidation of purine nucleotides by pterin in vitro: one is the hydrogen abstraction reaction of electron transfer from dGMP to the triplet excited state of pterin (type I mechanism), and the other is the interaction between dGMP and pterin. The reaction produces singlet molecular oxygen (1O2) (Type II mechanism) .
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- HY-103388
-
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COX
TGF-β Receptor
Glutathione Peroxidase
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Inflammation/Immunology
|
NCX 466 is an orally active COX-1 and COX-2 inhibitor that exhibits anti-inflammatory and analgesic effects. Additionally, NCX 466 acts as a NO donor, exerting anti-inflammatory and antioxidant effects by improving microcirculation. NCX 466 significantly reduces the levels of transforming growth factor-β (TGF-β) and oxidative stress markers (such as thiobarbituric acid reactive substances (TBARS) and 8-hydroxy-2'-deoxyguanosine (8-OHdG)), and it decreases leukocyte recruitment during inflammation by reducing myeloperoxidase (MPO) activity, thereby preventing bleomycin (HY-108345)-induced pulmonary fibrosis in mice .
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- HY-N0097A
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AraG
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Drug Derivative
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Cancer
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9-β-D-Arabinofuranosylguanine is a Guanosine (HY-N0097) analog and shows high affinity for deoxyguanosine kinase (dGK) with a Km of 8.0 μM. 9-β-D-Arabinofuranosylguanine can be used for the research of T-cell lymphoblastic disease .
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- HY-142028A
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AcycloGTP sodium
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DNA/RNA Synthesis
Nucleoside Antimetabolite/Analog
HIV
Reverse Transcriptase
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Infection
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Acyclovir triphosphate (Synonyms: AcycloGTP) sodium is a Acyclovir (HY-17422) derivative that competitively inhibits viral DNA polymerase by acting as an analog to deoxyguanosine triphosphate (dGTP). Acyclovir triphosphate sodium is an inhibitor of HIV-1 reverse transcriptase. Acyclovir triphosphate sodium causes termination of viral DNA synthesis .
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- HY-132144A
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Biochemical Assay Reagents
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Others
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7-Deaza-7-propargylamino-dGTP sodium is the sodium salt form of 7-Deaza-7-propargylamino-dGTP (HY-132144). 7-Deaza-7-propargylamino-dGTP sodium is an analog of deoxyguanosine triphosphate dGTP (HY-W008661) and can be used for gene sequencing .
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- HY-154478
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Nucleoside Antimetabolite/Analog
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Cancer
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3’-O-Acetyl-N2-iso-Butyroyl-2’-deoxy-guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-P5443
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Bacterial
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Others
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Pyrrhocoricin is a biological active peptide. (Antimicrobial activity against Gram-negative bacteria)
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- HY-17365
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Cat. No. |
Product Name |
Type |
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- HY-W048492
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7-Deaza-7-Iodo-2'-Deoxyguanosine
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Gene Sequencing and Synthesis
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7-Iodo-7-deaza-2'-deoxyguanosine (7-Deaza-7-Iodo-2'-deoxyguanosine) is a deoxyguanosine derivative that can be used in DNA synthesis and sequencing reactions .
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- HY-W008661
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dGTP (trisodium) solution (100mM); 2'-Deoxyguanosine-5'-triphosphate (trisodium) solution (100mM)
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Gene Sequencing and Synthesis
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Deoxyguanosine triphosphate (dGTP) trisodium solution (100mM) is a nucleotide precursor in cells for DNA synthesis. Deoxyguanosine triphosphate trisodium salt is used in reverse transcription-polymerase chain reaction (RT-PCR) for DNA amplification .
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- HY-132144
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Gene Sequencing and Synthesis
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7-Deaza-7-propargylamino-dGTP is an analog of deoxyguanosine triphosphate (dGTP) that can be used for gene sequencing .
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- HY-W008661A
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dGTP trisodium,100 mM Solution,PCR Grade; 2'-Deoxyguanosine-5'-triphosphate trisodium,100 mM Solution,PCR Grade
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Cell Assay Reagents
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Deoxyguanosine triphosphate trisodium,100 mM Solution,PCR Grade (dGTP trisodium,100 mM Solution,PCR Grade) is one of the raw materials used by DNA polymerase to synthesize long DNA chains during DNA replication. Deoxyguanosine triphosphate trisodium,100 mM Solution,PCR Grade (dGTP trisodium,100 mM Solution,PCR Grade) is used in reverse transcription polymerase chain reaction (RT-PCR) for DNA amplification. This product is provided in the form of aqueous solution .
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- HY-132140
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Gene Sequencing and Synthesis
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7-Deaza-7-propargylamino-3'-azidomethyl-dGTP is an analog of deoxyguanosine triphosphate (dGTP) that widely used in the next generation sequencing (NGS) .
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- HY-142028A
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AcycloGTP sodium
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Gene Sequencing and Synthesis
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Acyclovir triphosphate (Synonyms: AcycloGTP) sodium is a Acyclovir (HY-17422) derivative that competitively inhibits viral DNA polymerase by acting as an analog to deoxyguanosine triphosphate (dGTP). Acyclovir triphosphate sodium is an inhibitor of HIV-1 reverse transcriptase. Acyclovir triphosphate sodium causes termination of viral DNA synthesis .
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- HY-132144A
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Gene Sequencing and Synthesis
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7-Deaza-7-propargylamino-dGTP sodium is the sodium salt form of 7-Deaza-7-propargylamino-dGTP (HY-132144). 7-Deaza-7-propargylamino-dGTP sodium is an analog of deoxyguanosine triphosphate dGTP (HY-W008661) and can be used for gene sequencing .
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Cat. No. |
Product Name |
Target |
Research Area |
Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
Cat. No. |
Product Name |
Chemical Structure |
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- HY-17563S2
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2'-Deoxyguanosine- 13C10 (Deoxyguanosine- 13C10; Guanine deoxyriboside- 13C10) is 13C-labeled 2'-Deoxyguanosine (HY-17563). 2'-Deoxyguanosine (Deoxyguanosine) is deoxyguanosine.
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- HY-D0185S4
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2'-Deoxyguanosine- 13C10, 15N5 (monohydrate) is the 13C and 15N labeled 2'-Deoxyguanosine monohydrate . 2'-Deoxyguanosine monohydrate is an endogenous metabolite.
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- HY-17563S3
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2'-Deoxyguanosine-d13 (Deoxyguanosine-d13; Guanine deoxyriboside-d13) is deuterium labeled 2'-Deoxyguanosine (HY-17563). 2'-Deoxyguanosine (Deoxyguanosine) is deoxyguanosine.
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- HY-D0185S1
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2'-Deoxyguanosine-d (monohydrate) is the deuterium labeled 2'-Deoxyguanosine monohydrate. 2'-Deoxyguanosine monohydrate is an endogenous metabolite .
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- HY-D0185S
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2'-Deoxyguanosine-d2 (monohydrate) is the deuterium labeled 2'-Deoxyguanosine monohydrate. 2'-Deoxyguanosine monohydrate is an endogenous metabolite .
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- HY-W753153
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O-6-Methyl-2'-deoxyguanosine-d3 is the deuterium labeled O-6-Methyl-2'-deoxyguanosine.
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- HY-W767614
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O6-(2-Hydroxypropyl)-2'-deoxyguanosine-d3 is the deuterium labeled O6-(2-Hydroxypropyl)-2'-deoxyguanosine.
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- HY-W721188
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2'-Deoxy-N-ethylguanosine-d6 (N2-Ethyl-2'-deoxyguanosine-d6) is the deuterium labeled 2-(Ethylamino)-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one (HY-W013267).
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- HY-17563S4
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2'-Deoxyguanosine- 15N5 (Deoxyguanosine- 15N5; Guanine deoxyriboside- 15N5) is 15N labeled 2'-Deoxyguanosine (HY-17563). 2'-Deoxyguanosine (Deoxyguanosine) is deoxyguanosine.
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- HY-W338294S2
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2'-Deoxyguanosine- 13C (monohydrate) Monohydrate is the 13C labeled 2'-Deoxyguanosine .
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- HY-17563S
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2'-Deoxyguanosine- 13C, 15N2 (Deoxyguanosine- 13C, 15N2; Guanine deoxyriboside- 13C, 15N2) is the 13C- and 15N-labeled labeled 2'-Deoxyguanosine (HY-17563). 2’-Deoxyguanosine (Deoxyguanosine) is a purine nucleoside with a variety of biological activities. 2’-Deoxyguanosine can induce DNA division in mouse thymus cells. 2’-Deoxyguanosine is a potent cell division inhibitor in plant cells .
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- HY-W011540S
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8-Hydroxy-2'-deoxyguanosine- 15N5 is the 15N labeled 8-Hydroxy-2'-deoxyguanosine . 8-Hydroxy-2'-deoxyguanosine is a critical biomarker of oxidative stress and carcinogenesis .
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- HY-W653916
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8-Hydroxy-2'-deoxyguanosine- 13C, 15N2 is 13C and 15N labeled 8-Hydroxy-2'-deoxyguanosine. 8-Hydroxy-2'-deoxyguanosine is a critical biomarker of oxidative stress and carcinogenesis .
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- HY-W013159S
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2'-Deoxyguanosine 5'-monophosphate- 13C10, 15N5 (dGMP- 13C10, 15N5) disodium is the 13C and 15N labeled 2'-Deoxyguanosine 5'-monophosphate disodium (HY-W013159). 2'-Deoxyguanosine 5'-monophosphate (5′-dGMP) disodium is a mononucleotide having guanine as the nucleobase. 2'-Deoxyguanosine 5'-monophosphate disodium is a reactant involved in analysis of self-assembling in solution and nucleation/growth of G-qudruplexes, nucleophilic trapping and reductive alkylation. 2'-Deoxyguanosine 5'-monophosphate disodium can be used as an oxidizable target. 2'-Deoxyguanosine 5'-monophosphate disodium is a nucleic acid guanosine triphosphate (GTP) derivative and is a nucleotide precursor used in DNA synthesis .
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- HY-W768213
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2'-Deoxyguanosine monohydrate- 13C5 is the 13C-labeled 2'-Deoxyguanosine monohydrate (HY-D0185). 2'-Deoxyguanosine monohydrate is a nucleoside composed of guanine and deoxyribose, and is one of the basic building blocks of DNA. In the oxidation reaction mediated by singlet oxygen 1O2, the guanine base of 2'-Deoxyguanosine is easily oxidized to generate two major products, 4,8-dihydro-4-hydroxy-8-oxodG and 7,8-dihydro-8-oxodG. The oxidation products of 2'-Deoxyguanosine monohydrate may participate in DNA damage, which may affect gene expression or induce cancer .
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- HY-17563S1
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2'-Deoxyguanosine- 13C10, 15N5 (Deoxyguanosine- 13C10, 15N5; Guanine deoxyriboside- 13C10, 15N5) is a 13C- and 15N-labeled 2'-Deoxyguanosine (HY-17563).
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- HY-W393970S4
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2′-Deoxyguanosine 5′-monophosphate- 15N5 (5'-Deoxyguanylic acid- 15N5) dilithium is 15N labeled 2′-Deoxyguanosine 5′-monophosphate (HY-W393970).
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- HY-W393970S1
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2′-Deoxyguanosine 5′-monophosphate-d12 (5'-Deoxyguanylic acid-d12) dilithium is deuterium labeled 2′-Deoxyguanosine 5′-monophosphate (HY-W393970).
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- HY-W393970S2
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2′-Deoxyguanosine 5′-monophosphate- 13C10 (5'-Deoxyguanylic acid- 13C10) dilithium is 13C-labeled 2′-Deoxyguanosine 5′-monophosphate (HY-W393970).
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- HY-W767399
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8-Bromo-2'-deoxyguanosine- 13C, 15N2 is the 13C- and 15N-labeled 8-Bromo-2'-deoxyguanosine (HY-W011168). 8-Bromo-2'-deoxyguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-W393970S3
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2′-Deoxyguanosine 5′-monophosphate- 13C10, 15N5 (5'-Deoxyguanylic acid- 13C10, 15N5) dilithium is 13C and 15N-labeled 2′-Deoxyguanosine 5′-monophosphate (HY-W393970).
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- HY-W393970S
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2′-Deoxyguanosine 5′-monophosphate- 15N5,d12 (5'-Deoxyguanylic acid- 15N5,d12) dilithium is deuterium and 15N labeled 2′-Deoxyguanosine 5′-monophosphate (HY-W393970).
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- HY-138616S1
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dGTP-d14 (2'-Deoxyguanosine-5'-triphosphate-d14) dilithium is deuterium labeled dGTP (HY-138616). dGTP (2'-Deoxyguanosine-5'-triphosphate), a guanosine nucleotide, can be used in deoxyribonucleic acid synthesis. Guanosine nucleotides (GDP, GTP, dGDP, and dGTP) are highly susceptible to oxidative damage to 8-oxo-GDP (8-O-GDP), 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.
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- HY-138616S3
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dGTP- 13C10 (2'-Deoxyguanosine-5'-triphosphate- 13C10) dilithium is 13C-labeled dGTP (HY-138616). dGTP (2'-Deoxyguanosine-5'-triphosphate), a guanosine nucleotide, can be used in deoxyribonucleic acid synthesis. Guanosine nucleotides (GDP, GTP, dGDP, and dGTP) are highly susceptible to oxidative damage to 8-oxo-GDP (8-O-GDP), 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.
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- HY-138616S
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dGTP- 15N5 (2'-Deoxyguanosine-5'-triphosphate- 15N5) dilithium is 15N labeled dGTP (HY-138616). dGTP (2'-Deoxyguanosine-5'-triphosphate), a guanosine nucleotide, can be used in deoxyribonucleic acid synthesis. Guanosine nucleotides (GDP, GTP, dGDP, and dGTP) are highly susceptible to oxidative damage to 8-oxo-GDP (8-O-GDP), 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.
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- HY-138616S4
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dGTP- 13C10, 15N5 (2'-Deoxyguanosine-5'-triphosphate- 13C10, 15N5) dilithium is 13C and 15N-labeled dGTP (HY-138616). dGTP (2'-Deoxyguanosine-5'-triphosphate), a guanosine nucleotide, can be used in deoxyribonucleic acid synthesis. Guanosine nucleotides (GDP, GTP, dGDP, and dGTP) are highly susceptible to oxidative damage to 8-oxo-GDP (8-O-GDP), 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.
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- HY-138616S2
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dGTP- 15N5,d14 (2'-Deoxyguanosine-5'-triphosphate- 15N5,d14) dilithium is deuterium and 15N labeled dGTP (HY-138616). dGTP (2'-Deoxyguanosine-5'-triphosphate), a guanosine nucleotide, can be used in deoxyribonucleic acid synthesis. Guanosine nucleotides (GDP, GTP, dGDP, and dGTP) are highly susceptible to oxidative damage to 8-oxo-GDP (8-O-GDP), 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.
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- HY-13637S
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Ganciclovir-d5 is the deuterium labeled Ganciclovir. Ganciclovir (BW 759), a nucleoside analogue, is an orally active antiviral agent with activity against CMV. Ganciclovir also has activity in vitro against members of the herpes group and some other DNA viruses. Ganciclovir inhibits the in vitro replication of human herpes viruses (HSV 1 and 2, CMV) and adenovirus serotypes 1, 2, 4, 6, 8, 10, 19, 22 and 28. Ganciclovir has an IC50 of 5.2 μM for feline herpesvirus type-1 (FHV-1) .
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Cat. No. |
Product Name |
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Classification |
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- HY-132140A
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Azide
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7-Deaza-7-propargylamino-3'-azidomethyl-dGTP triethylamine is an analog of deoxyguanosine triphosphate (dGTP) that widely used in the next generation sequencing (NGS) .
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- HY-131803
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Azide
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Urolignoside is an antioxidant with free radical scavenging activity. Urolignoside potently scavenges DPPH radical, and exhibits antioxidant to β-carotene-lineoleate model . 3'-Azido-3'-deoxyguanosine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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Cat. No. |
Product Name |
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Classification |
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- HY-17563
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Deoxyguanosine; Guanine deoxyriboside
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Nucleosides and their Analogs
G
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2’-Deoxyguanosine (Deoxyguanosine) is a purine nucleoside with a variety of biological activities. 2’-Deoxyguanosine can induce DNA division in mouse thymus cells. 2’-Deoxyguanosine is a potent cell division inhibitor in plant cells .
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- HY-W048492
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7-Deaza-7-Iodo-2'-Deoxyguanosine
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Nucleosides and their Analogs
G
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7-Iodo-7-deaza-2'-deoxyguanosine (7-Deaza-7-Iodo-2'-deoxyguanosine) is a deoxyguanosine derivative that can be used in DNA synthesis and sequencing reactions .
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- HY-W013159
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5′-dGMP disodium
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Nucleotides and their Analogs
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2'-Deoxyguanosine 5'-monophosphate (5′-dGMP) disodium is a mononucleotide having guanine as the nucleobase. 2'-Deoxyguanosine 5'-monophosphate disodium is a reactant involved in analysis of self-assembling in solution and nucleation/growth of G-qudruplexes, nucleophilic trapping and reductive alkylation. 2'-Deoxyguanosine 5'-monophosphate disodium can be used as an oxidizable target. 2'-Deoxyguanosine 5'-monophosphate disodium is a nucleic acid guanosine triphosphate (GTP) derivative and is a nucleotide precursor used in DNA synthesis .
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- HY-W011540
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- HY-D0185
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Nucleosides and their Analogs
G
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2'-Deoxyguanosine monohydrate is a nucleoside composed of guanine and deoxyribose, and is one of the basic building blocks of DNA. In the oxidation reaction mediated by singlet oxygen 1O2, the guanine base of 2'-Deoxyguanosine is easily oxidized to generate two major products, 4,8-dihydro-4-hydroxy-8-oxodG and 7,8-dihydro-8-oxodG. The oxidation products of 2'-Deoxyguanosine monohydrate may participate in DNA damage, which may affect gene expression or induce cancer .
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- HY-18762
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6-thio-dG; β-TGdR
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Nucleosides and their Analogs
G
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6-Thio-2'-Deoxyguanosine is a nucleoside analogue that can be incorporated into de novo-synthesized telomeres by telomerase.
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- HY-W016011
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N2-Isobutyryl-2'-Deoxyguanosine
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Nucleosides and their Analogs
G
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iBu-dG (N2-Isobutyryl-2'-deoxyguanosine) is a nucleoside analog that can be used to synthesize oligoribonucleotides .
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- HY-W008661
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dGTP (trisodium) solution (100mM); 2'-Deoxyguanosine-5'-triphosphate (trisodium) solution (100mM)
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Nucleotides and their Analogs
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Deoxyguanosine triphosphate (dGTP) trisodium solution (100mM) is a nucleotide precursor in cells for DNA synthesis. Deoxyguanosine triphosphate trisodium salt is used in reverse transcription-polymerase chain reaction (RT-PCR) for DNA amplification .
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- HY-148169
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- HY-152351
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Nucleosides and their Analogs
G
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8-Bromo-3’-deoxyguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-W011168
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Nucleosides and their Analogs
G
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8-Bromo-2'-deoxyguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-W013330
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Guanosine, 3'-deoxy-
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Nucleosides and their Analogs
G
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3′-Deoxyguanosine (Guanosine, 3'-deoxy-) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-152367
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Nucleosides and their Analogs
G
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8-Hydroxy-3’-deoxyguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-154243
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Nucleosides and their Analogs
G
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8-Methyl-2’-deoxyguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-152354
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Nucleosides and their Analogs
G
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8-Benzyloxy-3’-deoxyguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-154470
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Nucleosides and their Analogs
G
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8-Aza-2’-deoxyguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-W010702
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N2-Isobutyryl-5′-O-(4,4′-dimethoxytrityl)-2′-Deoxyguanosine
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Nucleosides and their Analogs
G
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5'-O-DMT-N2-ibu-dG (N2-Isobutyryl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyguanosine) is a deoxynucleoside which can be used in the preparation of oligonucleotides .
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- HY-138616
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2'-Deoxyguanosine-5'-triphosphate
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Nucleotides and their Analogs
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dGTP (2'-Deoxyguanosine-5'-triphosphate), a guanosine nucleotide, can be used in deoxyribonucleic acid synthesis. Guanosine nucleotides (GDP, GTP, dGDP, and dGTP) are highly susceptible to oxidative damage to 8-oxo-GDP (8-O-GDP), 8-O-dGTP, 8-O-GTP, and 8-O-dGTP .
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- HY-W425099
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Nucleoside Phosphoramidites
G
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2'-Deoxyguanosine-(N-iBu)-3'-methyl-phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
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- HY-W098689
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2'-Deoxy-N2-dimethylaminomethylene-guanosine
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Nucleosides and their Analogs
G
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Dmf-dg (2'-Deoxy-N2-dimethylaminomethylene-guanosine) is a deoxyguanosine (dG) nucleoside protected by the dimethylaminomethylamidine (DMF) base and can be used for oligonucleotide synthesis .
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- HY-132140A
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Nucleotides and their Analogs
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7-Deaza-7-propargylamino-3'-azidomethyl-dGTP triethylamine is an analog of deoxyguanosine triphosphate (dGTP) that widely used in the next generation sequencing (NGS) .
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- HY-154478
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Nucleosides and their Analogs
G
|
3’-O-Acetyl-N2-iso-Butyroyl-2’-deoxy-guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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