2'-Deoxyguanosine monohydrate

Name: 2'-Deoxyguanosine monohydrate
Brand: MedChemExpress
SKU: HY-D0185
Rating: 5.0 (4 reviews)

Cat. No.: HY-D0185 Purity: 99.70%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

2'-Deoxyguanosine monohydrate is an endogenous metabolite.

For research use only. We do not sell to patients.

2'-Deoxyguanosine monohydrate Chemical Structure

CAS No. : 312693-72-4

Size	Price	Stock	Quantity

Free Sample (0.1 - 0.5 mg)		Apply Now
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	USD 44	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 44	In-stock	Estimated Time of Arrival: December 31
Solid
1 g	USD 40	In-stock	Estimated Time of Arrival: December 31
5 g	USD 90	In-stock	Estimated Time of Arrival: December 31
10 g		Get quote
50 g		Get quote

or Bulk Inquiry

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 4 publication(s) in Google Scholar

Other Forms of 2'-Deoxyguanosine monohydrate:

2'-Deoxyguanosine In-stock
2'-Deoxyguanosine-d₂ monohydrate Get quote
2'-Deoxyguanosine-d monohydrate Get quote
2'-Deoxyguanosine-¹³C₁₀,¹⁵N₅ monohydrate Get quote

4 Publications Citing Use of MCE 2'-Deoxyguanosine monohydrate

Featured Recommendations

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Biological Activity
Purity & Documentation
Customer Review

Description

2'-Deoxyguanosine monohydrate is an endogenous metabolite.

IC₅₀ & Target

Human Endogenous Metabolite

Molecular Weight

285.26

Formula

C₁₀H₁₅N₅O₅

CAS No.

312693-72-4

Appearance

Solid

Color

White to off-white

SMILES

O[C@H]1C[C@H](N2C=NC3=C2N=C(NC3=O)N)O[C@@H]1CO.O

Structure Classification

Others

Initial Source

Endogenous metabolite

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 25 mg/mL (87.64 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.5056 mL	17.5279 mL	35.0557 mL
5 mM	0.7011 mL	3.5056 mL	7.0111 mL
10 mM	0.3506 mL	1.7528 mL	3.5056 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 1.25 mg/mL (4.38 mM); Clear solution

This protocol yields a clear solution of ≥ 1.25 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (12.5 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Protocol 2

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 1.25 mg/mL (4.38 mM); Clear solution

This protocol yields a clear solution of ≥ 1.25 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (12.5 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

DMSO +

Tween-80 +

Saline

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Calculation results:

Working solution concentration: mg/mL

Method for preparing stock solution: mg drug dissolved in μL DMSO (Stock solution concentration: mg/mL).

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).

Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.

If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.

Purity & Documentation

Purity: 99.70%

Select Batch:

Data Sheet (248 KB) SDS (393 KB)

COA (251 KB) HNMR (153 KB) RP-HPLC (253 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.5056 mL	17.5279 mL	35.0557 mL	87.6393 mL
	5 mM	0.7011 mL	3.5056 mL	7.0111 mL	17.5279 mL
	10 mM	0.3506 mL	1.7528 mL	3.5056 mL	8.7639 mL
	15 mM	0.2337 mL	1.1685 mL	2.3370 mL	5.8426 mL
	20 mM	0.1753 mL	0.8764 mL	1.7528 mL	4.3820 mL
	25 mM	0.1402 mL	0.7011 mL	1.4022 mL	3.5056 mL
	30 mM	0.1169 mL	0.5843 mL	1.1685 mL	2.9213 mL
	40 mM	0.0876 mL	0.4382 mL	0.8764 mL	2.1910 mL
	50 mM	0.0701 mL	0.3506 mL	0.7011 mL	1.7528 mL
	60 mM	0.0584 mL	0.2921 mL	0.5843 mL	1.4607 mL
	80 mM	0.0438 mL	0.2191 mL	0.4382 mL	1.0955 mL