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Isoforms Recommended:	ANGPTL3

Results for "

ANGPTL3

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ANGPTL (4) PCSK9 (1) Small Interfering RNA (siRNA) (1)
By Research Areas:	Cardiovascular Disease (1) Metabolic Disease (4)
Oligonucleotides:	Pre-designed siRNA Sets (1) Antisense Oligonucleotides (2) siRNAs (1)

Inhibitors & Agonists

Inhibitory Antibodies

Recombinant Proteins

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-163794

DC371739	ANGPTL PCSK9	Metabolic Disease
DC371739 is a potent and orally activity PCSK9 inhibitor. DC371739 decreases the mRNA expression of PCSK9 and ANGPTL3. DC371739 decreases the protein expression of PCSK9 and increases the protein expression of LDLR. DC371739 has the potential for the research of hyperlipidemia .

HY-P99194

Evinacumab REGN1500	ANGPTL Others	Cardiovascular Disease Metabolic Disease
Evinacumab (REGN1500) is a human anti-ANGPTL3 (angiopoietin-like protein 3) monoclonal antibody (IgG4 class antibody). Evinacumab reduces plasma lipids in dyslipidemic mice by blocking ANGPTL3. Evinacumab can be used in studies of homozygous familial hypercholesterolaemia (HoFH), refractory hypercholesterolaemia (both familial and non-familial) and severe hypertriglyceridaemia .

HY-153497A

Vupanorsen sodium IONIS ANGPT-L3Rx sodium; ISIS 703802 sodium	ANGPTL	Metabolic Disease
Vupanorsen (sodium) is an N-acetyl galactosamine-conjugated antisense oligonucleotide that inhibits Angiopoietin-like 3 (ANGPTL3) protein synthesis. Vupanorsen (sodium) lowers triglycerides and atherogenic lipoproteins.

HY-RS00692

ANGPTL3 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
ANGPTL3 Human Pre-designed siRNA Set A contains three designed siRNAs for ANGPTL3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

ANGPTL3 Human Pre-designed siRNA Set A ANGPTL3 Human Pre-designed siRNA Set A

HY-153497

Vupanorsen IONIS ANGPT-L3Rx; ISIS 703802	ANGPTL	Metabolic Disease
Vupanorsen is an N-acetyl galactosamine-conjugated antisense oligonucleotide that inhibits Angiopoietin-like 3 (ANGPTL3) protein synthesis. Vupanorsen lowers triglycerides and atherogenic lipoproteins.

Cat. No.	Product Name	Target	Research Area

HY-P99194

Evinacumab REGN1500	ANGPTL Inhibitory Antibodies	Cardiovascular Disease Metabolic Disease
Evinacumab (REGN1500) is a human anti-ANGPTL3 (angiopoietin-like protein 3) monoclonal antibody (IgG4 class antibody). Evinacumab reduces plasma lipids in dyslipidemic mice by blocking ANGPTL3. Evinacumab can be used in studies of homozygous familial hypercholesterolaemia (HoFH), refractory hypercholesterolaemia (both familial and non-familial) and severe hypertriglyceridaemia .

Species:	Human (4) Mouse (1) Cynomolgus (2)
Tag:	His (7) Avi (2)
Source:	HEK293 (5) Sf9 insect cells (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P7504

	ANGPTL3/Angiopoietin-like 3 Protein, Mouse (HEK293, His) rMuAngiopoietin-like Protein 3, His; ANGPTL3; Angiopoietin-like Protein 3	Mouse	HEK293
	ANGPTL3/Angiopoietin-like 3 Protein, Mouse (HEK293, His) is a mouse recombinant ANGPTL3 with a 10-His tag at the C-terminus. Angiopoietin-like Protein 3, Mouse (HEK293, His) is produced by Mammalian expression system and the target gene encoding Ser17-Thr455 is expressed.

HY-P7505

	ANGPTL3/Angiopoietin-like 3 Protein, Human (HEK293, His) rHuAngiopoietin-like Protein 3, His; ANGPTL3; Angiopoietin-like Protein 3	Human	HEK293
	ANGPTL3/Angiopoietin-like 3 Protein, Human (HEK293, His) plays an important role in lipoprotein metabolism.Angiopoietin-like Protein 3 acts as a dual inhibitor of lipoprotein lipase (LPL) and endothelial lipase (EL).Angiopoietin-like Protein 3 inhibits endothelial lipase hydrolysis of HDL-phospholipid (PL), thereby increasing HDL-PL levels.

HY-P78059

	ANGPTL3/Angiopoietin-like 3 Protein, Human (Biotinylated, HEK293, His-Avi) ANGPTL3; ANGPT5; ANG-5; Angiopoietin-5; FHBL2; ANL3; Angiopoietin-5; Angiopoietin-like Protein 3	Human	HEK293
	ANGPTL3/angiopoietin-like 3 protein is a hepatic factor that complexly regulates lipid and glucose metabolism.It stimulates plasma triglycerides by inhibiting lipoprotein lipase (LPL), inhibits TG clearance through PCSK6 and FURIN recruitment, is independent of proteolytic cleavage, and is not affected by GPIHBP1.ANGPTL3/Angiopoietin-like 3 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived ANGPTL3/Angiopoietin-like 3 protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P75580

	ANGPTL3/Angiopoietin-like 3 Protein, Human (sf9, His) Angiopoietin-5; ANG-5; ANGPTL3; ANGPT5; UNQ153/PRO179	Human	Sf9 insect cells
	ANGPTL3/angiopoietin-like 3 protein is a hepatic factor that complexly regulates lipid and glucose metabolism.It stimulates plasma triglycerides by inhibiting lipoprotein lipase (LPL), inhibits TG clearance through PCSK6 and FURIN recruitment, is independent of proteolytic cleavage, and is not affected by GPIHBP1.ANGPTL3/Angiopoietin-like 3 Protein, Human (sf9, His) is the recombinant human-derived ANGPTL3/Angiopoietin-like 3 protein, expressed by Sf9 insect cells , with C-His labeled tag.

HY-P700954

	ANGPTL3/Angiopoietin-like 3 Protein, Cynomolgus (HEK293, His) ANGPTL3; ANGPT5; ANG-5; Angiopoietin-5; FHBL2; ANL3; Angiopoietin-5; Angiopoietin-like Protein 3	Cynomolgus	HEK293
	ANGPTL3/angiopoietin-like 3 protein is a hepatic factor that complexly regulates lipid and glucose metabolism. It stimulates plasma triglycerides by inhibiting lipoprotein lipase (LPL), inhibits TG clearance through PCSK6 and FURIN recruitment, is independent of proteolytic cleavage, and is not affected by GPIHBP1. ANGPTL3/Angiopoietin-like 3 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived ANGPTL3/Angiopoietin-like 3 protein, expressed by HEK293 , with C-His labeled tag. The total length of ANGPTL3/Angiopoietin-like 3 Protein, Cynomolgus (HEK293, His) is 444 a.a., with molecular weight of 60-70 kDa.

HY-P78379

	ANGPTL3/Angiopoietin-like 3 Protein, Human (HEK293, His-Avi) ANGPTL3; ANGPT5; ANG-5; Angiopoietin-5; FHBL2; ANL3; Angiopoietin-5; Angiopoietin-like Protein 3	Human	HEK293
	ANGPTL3/angiopoietin-like 3 protein is a hepatic factor that complexly regulates lipid and glucose metabolism.It stimulates plasma triglycerides by inhibiting lipoprotein lipase (LPL), inhibits TG clearance through PCSK6 and FURIN recruitment, is independent of proteolytic cleavage, and is not affected by GPIHBP1.ANGPTL3/Angiopoietin-like 3 Protein, Human (HEK293, His-Avi) is the recombinant human-derived ANGPTL3/Angiopoietin-like 3 protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P76726

	ANGPTL3/Angiopoietin-like 3 Protein, Cynomolgus (sf9, His) Angiopoietin-related protein 3; Angiopoietin-5; ANG-5; ANGPT5	Cynomolgus	Sf9 insect cells
	ANGPTL3/Angiopoietin-like 3 is a vascular growth factor and a member of the angiopoietin like protein family. It has high specificity for endothelial cells, performs various other regulatory activities to affect inflammation, and has been proved to have atherosclerosis promoting and atherosclerosis protective effects. NGPTL3/Angiopoietin-like 3 can also inhibit the activity of lipoprotein lipase and induce angiogenesis. ANGPTL3/Angiopoietin-like 3 Protein, Cynomolgus (sf9, His) is the recombinant cynomolgus-derived ANGPTL3/Angiopoietin-like 3 protein, expressed by Sf9 insect cells , with C-His labeled tag.

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HY-P82271

	ANGPTL3 Antibody (YA2016) ANG5; Angiopoietin 5; Angiopoietin like 3; ANGPT5; ANGPTL3; ANL3; FHBL2	WB, ICC/IF	Human, Mouse, Rat
	ANGPTL3 Antibody (YA2016) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2016), targeting ANGPTL3, with a predicted molecular weight of 54 kDa (observed band size: 54 kDa). ANGPTL3 Antibody (YA2016) can be used for WB, ICC/IF experiment in human, mouse, rat background.

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Cat. No.	Product Name		Classification

HY-153497A

Vupanorsen sodium IONIS ANGPT-L3Rx sodium; ISIS 703802 sodium		Antisense Oligonucleotides
Vupanorsen (sodium) is an N-acetyl galactosamine-conjugated antisense oligonucleotide that inhibits Angiopoietin-like 3 (ANGPTL3) protein synthesis. Vupanorsen (sodium) lowers triglycerides and atherogenic lipoproteins.

HY-RS00692

ANGPTL3 Human Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
ANGPTL3 Human Pre-designed siRNA Set A contains three designed siRNAs for ANGPTL3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-153497

Vupanorsen IONIS ANGPT-L3Rx; ISIS 703802		Antisense Oligonucleotides
Vupanorsen is an N-acetyl galactosamine-conjugated antisense oligonucleotide that inhibits Angiopoietin-like 3 (ANGPTL3) protein synthesis. Vupanorsen lowers triglycerides and atherogenic lipoproteins.

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